We report a case of multinodular thyroid goiter in an 80-year-old man who successfully underwent tracheal stent placement for respiratory distress caused by the thyroid goiter and following two radiofrequency (RF) ablation sessions performed for thyroid volume reduction. This sequential treatment allowed elective stent removals four weeks after the second RF ablation session because the thyroid...

We report a 55-year-old female who presented with trochanteric fracture of right femur. Examination and investigation revealed a huge retrosternal goiter with compression of great vessels which was asymptomatic for more than two decades. Subsequent investigation confirmed it as a case of toxic multinodular goitre with subclinical hyperthyroidism which is the possible cause of secondary osteopor...

This study aims to look at the prevalence of thyroid malignancy in previously healthy children and adolescents presented with multinodular goiter (MNG) and or solitary nodules for which they underwent thyroid surgery. Twenty one children and adolescents (13 males and 8 females) underwent partial or total thyroidectomy over a 10-year period. Papillary thyroid carcinoma was found in 4 (19%) patie...

Three groups of patients who had undergone subtotal thyroidectomy for Graves's disease, toxic multinodular goitre, or euthyroid multinodular goitre 12 to 15 years before and in whom a normal serum thyroxine (T-4) level was found were each divided into two subgroups on the basis of a normal or a raised serum thyrotrophin concentration. There was no difference in mean serum T-4 concentration betw...

Resistance to thyroid hormone (RTH) is an extremely rare dominantly inherited condition of impaired tissue responsiveness to thyroid hormone (TH). Most patients with RTH have mutations in the gene that encodes the β isoform of the receptor of thyroid hormone (THR-β gene). Mutant receptors are unable to activate or repress target genes. The majority of them are asymptomatic or rarely have hypo- ...

A postmenopausal female presented with an enlarging multinodular goiter. Microcalcifications within the largest thyroid nodule found by ultrasound prompted her to elect a total thyroidectomy. Histopathologic evaluation led to the diagnosis of confined papillary thyroid carcinoma (follicular variant). Elevated serum thyroglobulin levels were noted on postoperative laboratory workup, with the dif...

Retrosternal (intrathoracic) goiter has a prevalence of 4 to 20% of patients undergoing thyroidectomy for multinodular goiter. Although it is a condition affecting the older patient with a peak incidence in the sixth decade, the majority should be treated surgically. With few exceptions the operation can be safely accomplished through a cervical approach, only a small minority (approximately 2%...

HYPOTHESIS Multinodular goiter (MG) with compression symptoms has a clinical profile different from that of goiter without these symptoms. The surgical treatment of MG with compression symptoms has a high rate of sternotomy and morbidity. DESIGN Retrospective study conducted between 1970 and 1999. SETTING Tertiary referral center. PATIENTS One hundred fifty-seven patients with MG with com...

INTRODUCTION Thyroid carcinoma represents total 1 % of human neoplasm with increasing incidence for the last 4 decades. However, that increase appears to be due to an increase in the diagnosis of papillary microcarcinomas associated with increased sampling of 1 resected specimens by pathologists . Epidemiologically ascertained risk factors are ionising radiation, the presence of thyroid adenoma...