изучить клиническое течение туляремии и везикулезного риккетсиоза на современном этапе в Донбассе research of tularemia and vesicular rickettsiosis current clinical course in Donbass

There are three families of vesicular neurotransmitter transporters. The vesicular amine transporters (VATs) are members of the toxin-extruding protontranslocating antiporter family (TEXANs) (1). The vesicular inhibitory amino acid transporter (VIAAT/ VGAT) is a member of a second family with limited homology to plant amino acid permeases (2, 3). A vesicular transporter for the excitatory amino...

The allele Mx regulates the extent to which interferon alpha/beta inhibits the growth of influenza viruses in mouse cells such as peritoneal macrophages. The time course of induction of the antiviral state against an influenza A virus is comparable in macrophages with and without Mx and is similar to that found with vesicular stomatitis virus. In contrast, the decay of the antiviral state again...

Though the general appearance and the cellular composition of the pancreatic islets of the Mongolian gerbil (Meriones unguiculatus) conformed to those of most other rodent species, some peculiar ultrastructural details were found. Thus there were diversiform, mainly vesicular particles with varying electron opacity in these islets. The vesicular particles showed a clear association to cilia whi...

Eukaryotic cells contain membrane-less organelles, including nucleoli and stress granules, that behave like liquid droplets. Such endogenous condensates often have internal substructure, but how this is established in the absence of membrane encapsulation remains unclear. We find that the N- and C-terminal domains of TDP43, a heterogeneous nuclear ribonucleoprotein implicated in neurodegenerati...

Un cuadro de meningitis aséptica, en el contexto un paciente inmunosuprimido con diagnóstico infección por Virus Inmunodeficiencia Humana (VIH), debe llevar a pensar múltiples diagnósticos diferenciales. Entre estos, se incluye virus varicela zóster (VVZ) como uno los principales agentes causales líquido cefalorraquídeo claro. Su reactivación da lugar manifestaciones neurológicas potencialmente...

Vesicular lipoproteins (e.g., lipoprotein-X) are found in plasma in cholestasis or following infusion of Intralipid or phospholipid. To investigate the metabolism of vesicular lipoproteins, we isolated them from the plasma of subjects with cholestasis or following chronic or single Intralipid infusion. Cholestasis and chronic Intralipid therapy were found to be associated with elevated plasma c...

Vesicular neurotransmitter transporters package transmitter into the lumen of synaptic vesicles for quantal release. However, the number of transporters that localize to each vesicle is not known. In this issue of Neuron, a study by Daniels et al. using the Drosophila neuromuscular junction and mutations of the vesicular glutamate transporter suggests that one transporter may suffice to fill ea...

Simultaneous measurements of IVIEC and SCA by two nanotip electrodes allows direct dynamic comparison between vesicular transmitter content release to shed light on stimulation-induced plasticity.