نتایج جستجو برای: mthfd1

تعداد نتایج: 113  

Journal: :International Journal of Molecular Sciences 2023

We investigated the association between methylenetetrahydrofolate reductase (gene MTHFR 677C>T, rs1801133), 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR 2756A>G, rs1805087), and dehydrogenase, cyclohydrolase formyltetrahydrofolate synthetase 1 MTHFD1 1958G>A, rs2236225)—well-studied functional variants involved in one-carbon metabolism—and gynecologic cancer risk, inter...

Journal: :Birth defects research. Part A, Clinical and molecular teratology 2014
Sibele Nascimento de Aquino Ryuichi Hoshi Elizabete Bagordakis Maria Giulia Rezende Pucciarelli Ana Camila Messetti Helenara Moreira Andreia Bufalino Andréa Borges Ana Lucia Rangel Luciano Abreu Brito Mario Sergio Oliveira Swerts Hercilio Martelli-Junior Sergio R Line Edgard Graner Sílvia R A Reis Maria Rita Passos-Bueno Ricardo D Coletta

BACKGROUND Polymorphisms within the MTHFR (rs2274976) and MTHFD1 (rs2236225) genes were previously associated with maternal susceptibility for having an offspring with nonsyndromic cleft lip with or without cleft palate (NSCL/P) in the Brazilian population. However, as the genotypes of the patients with NSCL/P were not evaluated, it is not clear whether the effects are associated with maternal ...

Journal: :Seizure 2012
Oğuzhan Öz Mehmet Yücel Hakan Akgün Zeki Gökçil Zeki Odabaşı

Increased asymmetric dimethylarginine level after antiepi-leptic drug treatment may be independent of the changes in plasma homocysteine level Dear Editor, We have read the recent article by Sniezawska and colleagues with great interest. 1 The authors investigated the frequency of polymorphism in the MTHFR (C677T), MTR (A2756G), and MTHFD1 (G1958A) genes and analysed the levels of homocysteine ...

Journal: :Indian Journal of Medical Sciences 2022

Objectives: There are many multifactorial causes for Congenital Heart Defects (CHDs) in which both genetic and non-genetic factors play role. MTHFD1 CBS two of the key enzymes that plays pivotal role metabolic pathway homocysteine. Most studies revealed genes involved folate/homocysteine pathways occurrence CHDs. The present study was planned to investigate common polymorphisms gene children wi...

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