High-density lipoprotein (HDL) is a lipid and protein complex that consists of apolipoproteins and lower level HDL-associated enzymes. HDL dysfunction is a factor in atherosclerosis and decreases patient survival. Mass spectrometry- (MS-) based proteomics provides a high throughput approach for analyzing the composition and modifications of complex HDL proteins in diseases. HDL can be separated...

Electrospray ionization mass spectrometry (ESI MS) has emerged recently as a powerful tool for analyzing many structural and behavioral aspects of metalloproteins in great detail. In this review we discuss recent developments in the field, placing particular emphasis on the unique features of ESI MS that lend themselves to metalloprotein characterization at a variety of levels. Direct mass meas...

Intact protein analysis via top-down mass spectrometry (MS) provides the unique capability of fully characterizing protein isoforms and combinatorial post-translational modifications (PTMs) compared to the bottom-up MS approach. Front-end protein separation poses a challenge for analyzing complex mixtures of intact proteins on a proteomic scale. Here we applied capillary electrophoresis (CE) th...

Metabolic syndrome (MS) is a cluster of cardiovascular risk factors such as hypertension, dyslipidemia, obesity and type II diabetes. Here, we performed a case-control study analyzing the association between 894G>T endothelial nitric oxide synthase gene polymorphism (NOS3) and MS in 616 subjects. Genotype frequencies were TT= 9.3%, GG= 37.2 and TG= 53.6% and the allelic frequencies were T=0.36 ...

Xanthates are commonly used collectors in flotation processes but highly toxic to the aquatic environment. However, there few methods for reliable determination of low xanthate concentrations water samples. In this work, a sensitive, selective, and fast method is presented potassium ethyl (KEX). KEX was determined by high-performance liquid chromatography–inductively coupled plasma–mass spectro...

Technology offers educators active learning and new teaching strategies. Five lower cost and scalable technology applications are presented as alternative or complement to high-fidelity simulation. Professional nurse educators should adopt technology when teaching and interact with vendors to generate real-world applications that advance development. J Contin Educ Nurs. 2018;49(3):105-108.

Australia: the healthiest country by 2020. Internet sites This work is copyright. You may download, display, print and reproduce this material in unaltered form only (retaining this notice) for your personal, non-commercial use or use within your organisation. Apart from any use as permitted under the Ms Tessa Letcher – writer and all Taskforce members

Carnegie Mellon University CMU and the Sarno Corporation Sarno are performing an integrated feasibility demonstration of Video Surveillance and Monitoring VSAM The ob jective is to develop a cooperative multi sensor video surveillance system that provides contin uous coverage over battle eld areas Signi cant achievements have been demonstrated during VSAM Demo I in November and in the interveni...

An automated solid-phase extraction-liquid chromatography- tandem mass spectrometry (SPE-LC-MS-MS) method using the Spark Holland Symbiosis Pharma SPE-LC coupled to a Waters Quattro Micro MS-MS was developed for the analysis of 6-acetylmorphine (6-AM) in human urine specimens. The method was linear (R² = 0.9983) to 100 ng/mL, with no carryover at 200 ng/mL. Limits of quantification and detectio...

OBJECTIVES Of the fourteen counties and two municipalities that until recently were responsible for healthcare provision in Denmark, five introduced mammography screening (MS) programs. The objective of this research is to explain this decision-making variation and to gain insight into priority setting processes in health-care provision at the county level in Denmark. METHODS Literature on pr...