background: it has been proposed that oxidative stress may contribute to the development of testicular abnormalities in diabetes. morus alba leaf extract (mae) has hypoglycemic and antioxidant properties. we, therefore, explored the impact of the administration of mae on steroidogenesis in diabetic rats. methods: to address this hypothesis, we measured the serum level of glucose, insulin, and f...

results the median level of pbmcs htert mrna in survivors increased with treatment time and was significantly higher than the corresponding level in non-survivors after 14 days of treatment (p < 0.001). subgroup analyses showed that the levels of pbmcs htert mrna were remarkably higher in patients with acute-on-chronic liver failure than in those with chronic liver failure (p < 0.05). in patien...

the mrna expression of growth hormone (gh) gene in early development stages of siberian sturgeon was investigated using rt-pcr method. samples were collected from unfertilized eggs up to 50 days post hatched (dph) larvae in 11 different times. ribosomal protein l6 (rpl6) transcripts were used as the internal standard during quantification of gh mrna expression. the results showed that the gh mr...

conclusions the obtained results indicate that rsm is an effective method for the optimization of culture conditions for hes gene expression in e. coli. results a maximum rhes mrna level of 376.16% was obtained under the following conditions: 0.6 mm iptg, 7 hours post-induction time, and 0.9 cell density before induction. the level of rhes mrna was significantly correlated with post-induction t...

multiple sclerosis is a chronic inflammatory disease of the central nervous system characterized by a complex immune response. because of the complex nature of ms pathogenesis, a panel of biomarkers derived from different platforms will be required to reflect disease-related alterations. monitoring and evaluation of molecules associated with the pathogenesis of the disease would provide useful ...