INTRODUCTION Patients with heart transplant are screened for silent graft rejection by recurrent endomyocardial biopsies. MRI can detect the presence of oedema non-invasively by quantitatively measuring changes of the transverse relaxation time T2 in the myocardium. Several monocentric studies have shown that T2 quantification could help detect graft rejection in a less invasive way. DRAGET is ...

this paper introduces a novel methodology for the segmentation of brain ms lesions in mri volumes using a new clustering algorithm named scpfcm.  scpfcm uses membership, typicality and spatial information to cluster each voxel. the proposed method relies on an initial segmentation of ms lesions in t1-w and t2-w images by applying scpfcm algorithm, and the t1 image is then used as a mask and is ...

Background: A brain magnetic state (in terms of magnetic susceptibility distribution χ) can be detected by T2*-weighted MRI (T2*MRI) undergoing a cascade of data transformations. The MRI transformations cause distortions (or spatial morphing), which may be undone by solving the inverse imaging or mapping problem. Upon having a dataset acquired from Blood Oxygenation Level-Dependent (BOLD) funct...

In MRI, the coherence lifetime T2 is sensitive to the magnetic environment imposed by tissue microstructure and biochemistry in vivo. Here we explore the possibility that the use of T2 relaxometry may provide information complementary to that provided by diffusion tensor imaging (DTI) in ageing of healthy controls (HC), Alzheimer's disease (AD) and mild cognitive impairment (MCI). T2 and diffus...

PURPOSE To develop a model-based reconstruction technique for T2 mapping based on multi-echo spin-echo MRI sequences with highly undersampled Cartesian data encoding. MATERIALS AND METHODS The proposed technique relies on a nonlinear inverse reconstruction algorithm which directly estimates a T2 and spin-density map from a train of undersampled spin echoes. The method is applicable to acquisi...

BACKGROUND Acute subarachnoid hemorrhage (SAH) has traditionally been diagnosed by computed tomography (CT); however, fluid-attenuated inversion recovery (FLAIR) is a magnetic resonance imaging (MRI) modality currently used to detect acute SAH. CT is insensitive in the detection of subacute or chronic SAH. The purpose of this study was to compare 4 MRI pulse sequences and CT in the detection of...

MRI has provided important insights into the pathophysiology of multiple sclerosis (MS).1 However, conventional MRI scans furnish only gross estimates of the nature and extent of tissue damage associated with MS,2 and the data correlate poorly with measures of concurrent disability in patients. Recent advances in MRI technology have improved the correlation of MRI findings with clinical status ...