نتایج جستجو برای: mri rat

تعداد نتایج: 379670  

Journal: :European cells & materials 2008
K J Saldanha S L Piper K M Ainslie H T Kim S Majumdar

Minimally-invasive monitoring of regeneration in diseased tissue is an important aspect of stem cell therapy. Magnetic resonance imaging (MRI) based tracking of cells labelled with ferumoxides has the potential for non-invasive in vivo detection and longitudinal assessment of implanted cells. Cells labelled with ferumoxides appear as hypointense regions on MR images and thus can be distinguishe...

Journal: :Rheumatology 2010
Jean C Goebel Radu Bolbos Martin Pham Laurent Galois Adrian Rengle Damien Loeuille Patrick Netter Pierre Gillet Olivier Beuf Astrid Watrin-Pinzano

OBJECTIVE To assess OA-related changes in mean compartmental femorotibial cartilage thickness in rat knees by three-dimensional (3D) MRI (7T). METHODS MRI was performed in vivo at 7T on OA and untouched contralateral knee joints. Gradient Echo Fast Imaging 3D MR images were acquired sequentially in surgically induced OA (D0) in 40 Wistar rats (anterior cruciate ligament transection). Mean fem...

Journal: :Magnetic resonance in medicine 2015
Meiyun Wang Xiaohua Hong Che-Feng Chang Qiang Li Bo Ma Hong Zhang Sinan Xiang Hye-Young Heo Yi Zhang Dong-Hoon Lee Shanshan Jiang Richard Leigh Raymond C Koehler Peter C M van Zijl Jian Wang Jinyuan Zhou

PURPOSE To explore the capability of amide proton transfer (APT) imaging in the detection of hemorrhagic and ischemic strokes using preclinical rat models. METHODS The rat intracerebral hemorrhage (ICH) model (n = 10) was induced by injecting bacterial collagenase VII-S into the caudate nucleus, and the permanent ischemic stroke model (n = 10) was induced by using a 4-0 nylon suture to occlud...

Journal: :International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2007
Yanxin Wang Pik-To Cheung Gary X Shen Inderjeet Bhatia Ed Xue Wu Deqiang Qiu Pek-Lan Khong

PURPOSE In a neonatal rat model of hypoxic-ischemic (HI) brain injury, using T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI), we aim to determine the best MRI method of lesion quantification that reflects infarct size. MATERIALS AND METHODS Twenty 7-day-old rats underwent MRI 24h after HI brain injury was induced. Lesion size relative to whole brain was measured using T2WI and...

Journal: :Stroke 1999
M Fujioka T Taoka Y Matsuo K I Hiramatsu T Sakaki

BACKGROUND AND PURPOSE Specific change of persistent hyperintensity/hypointensity on T1-weighted (T1W) and T2-weighted (T2W) MRI, respectively, has been reported to develop in the human basal ganglia after brief hemispheric ischemia. We investigated whether this ischemic change observed in humans could be reproduced experimentally in rats after brief middle cerebral artery (MCA) occlusion (MCAO...

پایان نامه :دانشگاه آزاد اسلامی - دانشگاه آزاد اسلامی واحد یزد - دانشکده پزشکی 1392

بعد از انتخاب کودکان به وسیله نمونه گیری آسان، اطلاعات مورد نیاز مانند اطلاعات دموگرافیک، سن شروع تشنج، نوع تشنج و ... و نیز اطلاعات پاراکلینیکی مانند نتایج سی تی اسکن، mri و eeg در پرسشنامه ای محقق ساخته جمع آوری شد. مقادیر به دست آمده بعد از جمع آوری مورد تجزیه و تحلیل آماری قرار گرفت یافته ها:میان موارد سی تی اسکن مثبت و mri مثبت 3/69% بود. فراوانی نسبی غیرطبیعی بودنmri بدون تزریق مغز در هر...

Journal: :Nanoscale Research Letters 2021

Abstract Parkinson's disease (PD) is characterized by the progressive loss of dopaminergic neurons in midbrain, and stem cell transplantation method provides a promising strategy for treatment. In these studies, tracking biological behaviors transplanted cells vivo essential basic understanding function evaluation clinical effectiveness. present study, we developed novel ultrasmall superparamag...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2006
Haiying Cheng Govind Nair Tiffany A Walker Moon K Kim Machelle T Pardue Peter M Thulé Darin E Olson Timothy Q Duong

MRI is a noninvasive diagnostic modality that reveals anatomy, physiology, and function in vivo without depth limitation or optical interference. MRI application to the retina, however, remains challenging. We improved spatial resolution to resolve layer-specific structure and functional responses in the retina and confirmed the laminar resolution in an established animal model of retinal degen...

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