With flexure-based micro-positioning stages (MPSs) being in high demand for high-precision applications, the performance and cost of MPSs are two issues that urgently need to be addressed. In addition, current developed toward complex spatial configurations, which further precludes monolithic fabrication. To address aforementioned issues, modular using designed standardized modules introduced t...

Data envelopment analysis (DEA) is a mathematical programming - based technique to evaluate the performance of homogeneous group decision-making units (DMUs) with multiple inputs and outputs. One DEA applications involves aggregating input resources reallocating them create efficient DMUs.The present study employs centralized resource allocation (CRA) approach develop model for creating new DMU...

All-trans retinoic acid (tRA) is a potent differentiation agent that is effective therapy for acute promyelocytic leukemia (APL). However, 5% to 25% of patients develop retinoic acid syndrome, a potentially life-threatening complication in which the pathogenesis relates to adhesive alterations of APL cells. Therefore, we investigated the relationship between tRA-induced differentiation and the ...

BACKGROUND Biliary leaks have been treated with endoscopic management using different techniques with conflicting results. Furthermore the appropriate rescue therapy for refractory leaks has not been established. We evaluated the clinical effectiveness of initial endotherapy for postcholecystectomy biliary leaks using an homogenous approach (sphincterotomy + placement of a 10-French plastic ste...

INTRODUCTION Diagnosis of the mucopolysaccharidoses (MPSs) generally relies on an initial analysis of total glycosaminoglycan (GAG) excretion in urine. Often the dimethylmethylene blue dye-binding (DMB) assay is used, although false-negative results have been reported. We report a multiplexed diagnostic test with a high sensitivity for all MPSs and with the potential to identify patients with I...

MOTIVATION With the expansion of whole-genome studies, there is rapid evolution of genotyping platforms. This leads to practical issues such as upgrading of genotyping equipment which often results in research groups having data from different platforms for the same samples. While having more data can potentially yield more accurate copy-number estimates, combining such data is not straightforw...

Background: Central nervous system (CNS) has limited repair capacity, and any spinal cord injury (SCI) can cause persistent disability in motor, sensory, autonomic functions. The harmful reactions around the lesion must be stopped to prevent this consequence. Objectives: present study compares clinical effects of methylprednisolone sodium succinate (MPSS) meloxicam acute an animal model rats. M...

In case of high-speed maglev trains, the propulsion force of their Linear Synchronous Motor (LSM) is an essential performance element since the LSM is responsible for both the propulsion and levitation of the train. A large thrust force ripple causes vibration, noise and severe levitation disturbance during the train operation. Because of these reasons, efforts must be made to reduce the thrust...

Previous studies suggest that chronic stress may induce immune system malfunction and a broad range of adverse health outcomes; however, the underlying pathways for this relationship are unclear. Our study aimed to elucidate this question by examining the relationship between parental cardiovascular risk factors including systolic blood pressure (SBP), diastolic blood pressure (DBP), body mass ...

AIM After acute spinal cord injury (SCI), a large number of axons are lost by a cascade of pathophysiological events known as a secondary injury. The main aim of the current study was to investigate the potential neuroprotective effects of curcumin on lipid peroxidation (LPO), neurological function, and ultrastructural findings after SCI. MATERIAL AND METHODS Forty adult Wistar albino rats we...