نتایج جستجو برای: mpe

تعداد نتایج: 1068  

2016
Chun Gao

Molecular pathological epidemiology (MPE) is a multidisciplinary and transdisciplinary study field, which has emerged as an integrated approach of molecular pathology and epidemiology, and investigates the relationship between exogenous and endogenous exposure factors, tumor molecular signatures, and tumor initiation, progression, and response to treatment. Molecular epidemiology broadly encomp...

2016
Faisal Faiyaz Zuberi Bader Faiyaz Zuberi Syed Khalid Ali Sagheer Hussain Farhana Mumtaz

OBJECTIVE To determine diagnostic yield of Closed Pleural Biopsy (CPB) and Cytology in Exudative Pleural Effusion (PE). METHODS This prospective comparative study was conducted at Chest Unit-II & Medical Unit-IV of Dow University of Health Sciences, Karachi Pakistan from January 2011 till December 2014. RESULTS Ninety-four patients with exudative PE were finally included. The mean age (SD) ...

2011
Mohan Appasaheb Dhale Vijayalakshmi Govindaswamy

The effect of Monascus purpureus extract (MPE) on probiotic lactic acid bacteria (LAB) was investigated to ascertain its application in fermented foods. Viable count of LAB was not affected after 24 hours of incubation in Man Rogosa Sharpe (MRS) broth containing MPE. The agar well-diffusion assay did not show any inhibition zone. The biotransformation of isoflavone glycosides by LAB in culture ...

2014
Simone Poddighe Francescaelena De Rose Roberto Marotta Roberta Ruffilli Maura Fanti Pietro Paolo Secci Maria Cristina Mostallino Maria Dolores Setzu Maria Antonietta Zuncheddu Ignazio Collu Paolo Solla Francesco Marrosu Sanjay Kasture Elio Acquas Anna Liscia Aamir Nazir

The fruit fly Drosophila melanogaster (Dm) mutant for PTEN-induced putative kinase 1 (PINK1B9) gene is a powerful tool to investigate physiopathology of Parkinson's disease (PD). Using PINK1B9 mutant Dm we sought to explore the effects of Mucuna pruriens methanolic extract (Mpe), a L-Dopa-containing herbal remedy of PD. The effects of Mpe on PINK1B9 mutants, supplied with standard diet to larva...

Gh Sepehri M Mobasher M Shamsi Meimandi N Ashrafgangui

The clinical usefulness of morphine for treatment of chronic pain is limited by development of tolerance. So many authors have proposed the co-administration of other drugs. This study was performed to evaluate the role of gabapentin on analgesic effect of morphine. Four groups of male rats (220-250 g) were examined for time latency using tail flick test: control, morphine (M), gabapentin (GB),...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2015
Stephen C Mack Sameer Agnihotri Kelsey C Bertrand Xin Wang David J Shih Hendrik Witt Nadia Hill Kory Zayne Mark Barszczyk Vijay Ramaswamy Marc Remke Yuan Thompson Marina Ryzhova Luca Massimi Wieslawa Grajkowska Boleslaw Lach Nalin Gupta William A Weiss Abhijit Guha Cynthia Hawkins Sidney Croul James T Rutka Stefan M Pfister Andrey Korshunov Melike Pekmezci Tarik Tihan Joanna J Philips Nada Jabado Gelareh Zadeh Michael D Taylor

PURPOSE Myxopapillary ependymoma (MPE) is a distinct histologic variant of ependymoma arising commonly in the spinal cord. Despite an overall favorable prognosis, distant metastases, subarachnoid dissemination, and late recurrences have been reported. Currently, the only effective treatment for MPE is gross-total resection. We characterized the genomic and transcriptional landscape of spinal ep...

Journal: :Journal of the National Cancer Institute 2008
Georgios T Stathopoulos Ioannis Psallidas Ardiana Moustaki Charalampos Moschos Androniki Kollintza Sophia Karabela Ilias Porfyridis Spyridoula Vassiliou Marilena Karatza Zongmin Zhou Myungsoo Joo Timothy S Blackwell Charis Roussos Daniel Graf Ioannis Kalomenidis

BACKGROUND Tumor cells in malignant pleural effusions (MPEs) are an important source of monocyte chemoattractant protein (MCP)-1. However, the role of tumor-derived MCP-1 in the pathogenesis and progression of MPE has not been determined. METHODS B16 mouse skin melanoma cells, which are deficient in MCP-1 expression, and mouse Lewis lung cancer (LLC) cells, which express high levels of MCP-1,...

Journal: :Diagnostic Pathology 2008
Sundus A Hussein Monalisa Sur

BACKGROUND Myxopapillary ependymomas (MPE) occur in the filum terminale of the spinal cord, but also present in extra-spinal locations such as subcutaneous tissue and brain. They are slow growing grade I gliomas. Areas of solid growth pattern with aggregates of cells with "epithelioid morphology" seen in MPE can mimic metastatic carcinoma. The presence of occasional cells with clear cytoplasm a...

2016
Qian Li Wenkui Sun Dongmei Yuan Tangfeng Lv Jie Yin Ehong Cao Xinwu Xiao Yong Song

Malignant pleural effusion (MPE) signifies a poor prognosis for patients with lung cancer. For treating physicians, the primary goals are to achieve sufficient control of MPE and minimize invasive intervention. Recombinant human mutant tumor necrosis factor-alpha (rhu-TNF) has been used in the treatment of MPE. The aim of our research was to evaluate the efficacy and safety of rhu-TNF applicati...

Journal: :Respiration; international review of thoracic diseases 2013
Jing Qi Daling Li Jing Feng Shuo Yang Yuan Su Min Fang Zheng Tan Huanzhong Shi XiYun Yan Feili Gong Fang Zheng

BACKGROUND Natural killer (NK) cells are lymphocytes of the innate immune system that play a crucial role in tumor immune surveillance. Accumulated data indicated that NK cells in the tumor microenvironment often display a suppressed function. However, the mechanism is not clear. OBJECTIVE In this study, the effects and relative mechanisms of malignant pleural effusion (MPE) from patients wit...

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