a case with two simultaneous dens invaginations (dis) and one dens evagination (de) in a permanent maxillary lateral incisor is reported for the first time in a 21-year-old girl. de known as talon cusp of the anterior teeth is a rare entity and its co-existence with di has been reported scarcely in the literature. simultaneous occurrence of two dis with one de has not been reported elsewhere. u...

Agenesis of multiple primary teeth is rare. A 6-year-old girl visited our department, in the absence of any other systemic abnormalities, on clinical and radiographic evaluation, it was revealed that she had only 6 primary teeth in her mouth. Maxillary and mandibular removable partial dentures were fabricated for prosthodontic rehabilitation. At the 6 months follow-up nutrition of the patient a...

Examination of an infant born after prenatal diagnosis of mosaic partial trisomy 17q2 showed the unique phenotypic features of this chromosomal abnormality, that is, frontal bossing, large mouth, brachyrhizomelia, and hexadactyly. Amniocentesis was performed because of polyhydramnios and ultrasound diagnosis of fetal craniofacial dysmorphology and rhizomelic shortening of the limbs. Chromosomal...

Rothia muciliaginosa (R. mucilaginosa) is a facultative, Gram-positive coccus that is considered to be part of the normal flora of the mouth and respiratory tract. There are sporadic reports of the organism causing endocarditis in patients with heart valve abnormalities, as well as meningitis, septicemia, and pneumonia associated with intravenous drug abuse. However, it is an unusual pathogen i...

Burning Mouth Syndrome (BMS) is a frequent disease characterized by a burning or painful sensation in the tongue and/or other oral sites without clinical mucosal abnormalities or lesions. The etiopathology is unknown although local, systemic and psychological factors have been connected with BMS. As this syndrome is a multifactorial disease, the diagnostic and therapeutic approach should be mul...

of the tube, as well as of its anterior and posterior lips. Walker Wood has recorded an analysis of the nasopharyngeal findings in about 650 cases examined, and his results are instructive and valuable. There were forty abnormalities, in fifteen the Eustachian tubes being bifid, and in three there were adventitious openings. He figures cases of mucous polypus in the mouth of the tube, fibroma o...

Oculo-auriculovertebral spectrum (OAVS) or the Goldenhar syndrome is a rare developmental disorder with plethora of congenital anomalies which mostly affects structures arising from the fi rst and the second branchial arches. The affected structures include cheekbone, jaws, mouth eyes, ear and vertebrae. The case which we are presenting here had classical features such as microsomia, unilateral...

Harlequin ichthyosis (HI)--the most severe form of keratinizing disorders, often lethal in the neonatal period--is characterized by a profound thickening of the keratin skin layer, a dense "armor"-like scale that covers the body, and contraction abnormalities of the eyes, ears, and mouth. In this issue of the JCI, Akiyama et al. report that mutations in ABCA12 caused defective lipid transport t...

Although considerable knowledge regarding the clinical and serological abnormalities associated with Systemic Lupus Erythematosus (SLE) is available, the eiiology of this disorder is not yet clear. However, there is ample evidence to suggest that immunological mechanisms of tissue injury are important in its Pathogenesis. The prevalence of SLE is 2-3 per 100,000, and the disorder is 9 times mor...

Restrictive dermopathy (RD) is a very rare and lethal congenital skin disease. It is inherited by an autosomal recessive pattern with characteristic features of abnormally rigid skin, generalized joint contractures (arthrogryposis), and dysmorphic facies consisting of downward slanting eyes, a small pinched nose, low-set ears, a fixed open mouth in the O-position, and micrognathia. We report on...