نتایج جستجو برای: mouse neurotrophic factor
تعداد نتایج: 1085516 فیلتر نتایج به سال:
Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)–resident protein that plays a crucial role in attenuating ER stress responses. Although MANF indispensable for the survival and function of mouse ?-cells, its precise human ?-cell development unknown. In this study, we show lack humans results diabetes due to increased stress, leading impaired function. ...
Transcriptional regulators and neurotrophic factors in the pathogenesis of Amyotrophic Lateral Sclerosis (ALS) Histopathological and biochemical studies in the G93A ALS mouse model and in ALS post mortem tissue THESIS submitted in partial fulfillment of the requirements for the degree-Doctor rerum naturalium-Parts of the thesis have been published or submitted previously in: milder impairment o...
In the 1980s, authors developed enzyme immunoassay (EIA) system for mouse nerve growth factor (NGF) to clarify its important physiological roles. Our EIA was a new and powerful tool measurement of extremely low levels NGF in vitro vivo, it contributed investigation into regulatory mechanism synthesis. After that, we demonstrated that compounds with molecular weight, such as 4-methylcatechol, wh...
Since multiple sclerosis (MS) is featured with widespread demyelination caused by autoimmune response, we investigated the recovery effects of F3.olig2 progenitors, established by transducing human neural stem cells (F3 NSCs) with Olig2 transcription factor, in myelin oligodendrocyte glycoprotein- (MOG-) induced experimental autoimmune encephalomyelitis (EAE) model mice. Six days after EAE indu...
Glial Cell Line-Derived Neurotrophic Factor Induces Cell Proliferation in the Mouse Urogenital Sinus
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