Intestinal structure of male adult African Green monkeys (Cercopithecus aethiops ssp vervets) was studied after 3'/2 yr of consuming diets containing 10% psyllium husk or cellulose. Scanning electron microscopy (SEM) identified mild damage (cellular swelling and disarray, and microvillar denudation and disarray) at villous tips throughout the small intestine in the psyllium-fed monkeys. The cel...

Assessment of morphological changes has more often been used in the diagnosis and assessment of intestinal pathology and development. Since methionine is widely used in nutritional and sports supplements and also there is not enough information about the effect of this amino acid on the gastrointestinal histomorphometry, the aim of this study was to assess the effect of methionine on the small ...

Background & Aim:  Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in clinical medicine. The adverse effects they produce in the gastrointestinal tract however, often limit their utility. Oxidative stress has been shown to occur in the small intestine in response to the oral administration of indomethacin. In view of this, the effect of thyme essential oil, an agent with anti-o...

Background & Aim:  Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in clinical medicine. The adverse effects they produce in the gastrointestinal tract however, often limit their utility. Oxidative stress has been shown to occur in the small intestine in response to the oral administration of indomethacin. In view of this, the effect of thyme essential oil, an agent with anti-o...

The main objective of this study was to determine the effect of fiber source and concentration on morphological characteristics, mucin staining pattern, and mucosal enzyme activities in the gastrointestinal tract of pigs. The experiment included 50 pigs from 10 litters weaned at 4 wk of age (BW 8.6 +/- 1.4 kg) and divided into 5 treatment groups. Diets containing fiber of various physico-chemic...

DDC (3,5-diethoxycarbonyl-1,4-dihydrocollidine)-fed mice are widely used as a model for cholestatic liver disease. We examined the expression of tight junction protein claudin subspecies by immunofluorescent histochemistry in small intestine and kidney tissues of mice fed a DDC diet for 12 weeks. In the small intestine, decreases in claudin-3, claudin-7 and claudin-15 were observed in villous e...

Intestinal changes, mainly in the jejunum, were investigated in 13 cases of malignant histiocytosis at necropsy and who had presented as lethal midline granuloma. Villous atrophy with crypt hyperplasia was observed in all cases, and a proliferation of atypical histiocytes was observed in seven cases. In the remaining cases, histiocytes with normal morphology increased in number. These findings ...

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the most frequent form of inflammatory bowel disease (ibd) in dogs is represented, histologically, by lymphoplasmacytic enteritis (lpe), a histological category, often associated with other morphologic alterations including lymphangiectasia (le). however, literature data on this latter topic are quite scarce and have mostly been obtained in single reports or in small series. currently, there ar...