<p class="abstract"><strong>Background:</strong> An adverse drug reaction (ADR) remains often underreported and leads to underestimated cause of morbidity mortality. ADR frequently manifests as cutaneous reactions (ACDRs) manifestations varies from mild acneiform eruption life threatening events like toxic epidermal necrolysis. Aim was study clinic-epidemiological pattern vari...

BACKGROUND Early recognition and treatment of meningococcal disease improves its outcome. Haemorrhagic rash is one of the most specific signs that parents can learn to recognise. OBJECTIVE To determine the percentage of parents able to recognise a haemorrhagic rash and perform the tumbler test. METHODS 123 parents of children consulting for mild injuries were interviewed about the significa...

Qadri I, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-221401 Description The drug reaction with eosinophilia and systemic symptoms (DRESS syndrome) is a potentially life-threatening drug-induced reaction characterised by a severe skin eruption, fever, haematological abnormalities (eosinophilia or atypical lymphocytes) and internal organ involvement (liver is the most common). These manifestat...

Introduction: While drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is known to be associated facial swelling, this edema can challenging identify. This study evaluates the utility of a physical examination finding, oblique earlobe crease, support diagnosis DRESS. Design: retrospective case-control in which dermatologists evaluated for presence an crease patients diagnose...

human brucellosis is common in developing countries and is a multi-system disease with a broad spectrum of clinical manifestations. cutaneous lesions associated with brucellosis have been rarely reported in the literature. here we present a case of a 32-year-old man with history of consumption of cheese made from raw milk seen with occurrence of pancytopenia and diffuse maculopapular rash durin...

fever accompanied by rash is a common finding in pediatric patients. although, in most cases, the disease is trivial, in some cases it may be the first and/or the sole manifestation of a serious and life threatening condition in patients. the spectrum of differential diagnosis is broad and many different infectious and some noninfectious agents cause this syndrome. to establish a timely diagnos...

In December 2014, an 18-year-old male presented to Harbor-UCLA Medical Center in Los Angeles, CA with a 3-day history of pruritic, maculopapular rash, which began on the wrists and arms and rapidly spread to the rest of his body, including his palms. Four days before the rash was noted, he had a temperature of 101°F, malaise, myalgia, and polyarthralgia. The arthralgia started in his right wris...