The Monod model is a classical microbiological model much used in microbiology, for example to evaluate biodegradation processes. The model describes microbial growth kinetics in batch culture experiments using three parameters: the maximal specific growth rate, the saturation constant and the yield coefficient. However, identification of these parameter values from experimental data is a chall...

In this paper, we consider a simple chemostat model involving a single species feeding on redundant substrate with a constant yield term. Many experiments indicate that very high substrate concentrations actually inhibit growth. Instead of assuming the prevalent Monod kinetics for growth rate of cells, we use a non-monotonic functional response function to describe the inhibitory effect. A deta...

The conversion of glycerol to 1,3-propanediol (1,3-PD) by Clostridium acetobutylicum ATCC 4259 was studied in an anaerobic culture using commercial glycerol as the sole carbon source. The objective of this study was to determine the best concentration of glycerol used for the production of 1,3-propanediol and to study the cell growth kinetics of Clostridium acetobutylicum ATCC 4259 using fermen...

Lactiplantibacillus plantarum is a Gram-positive bacterium that belongs to the lactic acid bacteria (LAB) group commonly used in food industry. To use this microorganism, high biomass concentration necessary, and models need be established for predicting improving its behavior along fermentation. However, current L. are applicable only one substrate. The growth of newly isolated strain 60-1 co-...

Although chemically defined media have been developed and widely used to study the expression of virulence factors in the model plant pathogen Pseudomonas syringae, it has been difficult to link specific medium components to the induction response. Using a chemostat system, we found that iron is the limiting nutrient for growth in the standard hrp-inducing minimal medium and plays an important ...

Xylitol is an extracellular sugar alcohol produced by the biological conversion of xylose through the fermentation process. The present study investigates the reaction kinetics of xylitol fermentation by considering the effect of substrate and product concentration on the microbial growth rate. A 3.5-L batch fermentation produced xylitol at different xylose concentrations and agitation speeds. ...

This paper discusses the challenges associated with reliable and optimal operation of perfusion bioreactors presents methods for modeling identification as well vision their integration. After presenting a generic model bioreactors, shows how to use concept basis flux modes uniquely compute reaction rates. The advantage this respect elementary nodes similar concepts in metabolic analysis is red...

Unstructured models for cell growth, xylose consumption and xylitol production were applied to describe the fermentation kinetics of using Candida tropicalis in synthetic medium,and non-detoxified oil palm empty fruit bunch (OPEFB) hydrolysate at 100 mL flask scale. In medium, experimental maximum specific growth rate (μmax) mass yield factor(YX/S) closer results Tessier model than those Contoi...

Monod kinetic parameters (Ks, micromax, and Y) that are estimated from batch experimental data can have large uncertainties due to linear correlations between them. The degree of correlation and the resulting uncertainties of the Monod parameters are functions of the initial experimental conditions, the values of the parameters, the type and magnitude of measurement errors, and the sampling num...