نتایج جستجو برای: monoclonal antibody
تعداد نتایج: 190951 فیلتر نتایج به سال:
SUMMARY Monoclonal Antibodies are identical antibodies and Can be generated in ultimated amounts by countinuos cultures of single antibody- secreting cells. These cell lines are produced by cell fusion of normal lymphocytes to cells of a myeloma tumor cell line, which confers on the antibody producing hybrid cell, immortality and the ability grow as atumor in animals. monoclonal antibodies c...
Background: Human cancer cell lines express human choriogonadotropin (hCG), its subunits and derivatives, regardless of their origin and type. It appears that hCG is a common phenotype in human cancer cell lines. In this research, the effects of hCG targeting monoclonal antibodies (7D9, T18H7 and T8B12) on human cancer cell lines were evaluated. Methods: Monoclonal antibody secreting hy...
Background and Objective: Lipoarabinomannan mannesylated (ManLAm) is one of the lipoglycans which forms a considerable percent of Mycobacterium Bovis BCG’ cellular wall. Considering that generation of monoclonal antibody against ManLAM antigen has many applications, specifically, in order to design the diagnostic kit for rapid diagnosing of tuberculosis, so the main objective of this study wa...
Abstract Background: Since the development of monoclonal antibodies by hybridoma technology the use of antibodies in targeted therapy has been considered. ScFv (single-chain variable fragment) is a small fragment of monoclonal antibody which binds to its target, especially. The goal of this study, is introducing of scFv, its production pathways as well as its diagnostic and therapeutic appl...
PR81 is a monoclonal antibody that binds with high affinity to MUC1 that over expressed on breast tumors. PR81 is considered a suitable targeting molecule that was radiolabeled using Cu-64 for positron imaging studies. The monoclonal antibody was conjugated with DOTA moiety and after purification was evaluated for radiochemical purity, immunoreactivity, cell toxicity and structure integrity as ...
a murine igm monoclonal antibody (ma-2c6) with κ-light chains directed against an antigenic determinant of outer surface protein a (ospa) of the lyme disease spirochete, borreliaburgdorferi, is produced. this antibody could bind specifically to ospa antigen of several isolates of b. burgdorferi, but not to the non-lyme disease bacteria such as t. pallidum and b. hermsii. antibody ma-2c6 was pur...
background: lung carcinoma is a multiple type cancer comprising of small cell and non-small cell carcinomas (nsclc). for therapeutic and diagnostic purposes, serum monoclonal antibodies have been produced against lung cancer. objective: to charac-terize a murine monoclonal antibody (me3d11) reactive with human nsclc. methods: a murine monoclonal antibody (me3d11) reactive with human nsclc was s...
چکیده ندارد.
radiolabeled monoclonal antibodies, have created new innovations in diagnosis, research and therapy of disease in last 2 decades. one of the serious limitation of applications of radiolabeled antibodies in vivo is relatively low target to background activity. various strategies have been proposed to solve this problem including pre-targeting methods that was suggested in 1989. regarding importa...
Objective(s):Multi-epitopic protein vaccines and direction of vaccine delivery to dendritic cells (DCs) are promising approaches for enhancing immune responses against mutable pathogens. Escherichia coli is current host for expression of recombinant proteins, and it is important to optimize expression condition. The aim of this study was the optimization of multi-epitopic HIV-1 tat/pol/gag/env ...
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