A molybdenum cofactor which is capable of reconstituting demolybdosulfite oxidase purified from livers of tungstentreated rats has been identified in rat liver and various organisms. Reconstitution with the rat liver cofactor is directly proportional to cofactor and demolybdoenzyme concentrations and proceeds most efficiently in 0.01 M potassium phosphate buffer, pH 7.4. The activation process ...

Background: With the spread of nanotechnology, various nanoparticles with new and emerging properties have been produced and the potential toxic effects of the majority of these particles remains still unknown. The present study was conducted to determine the toxicity of Molybdenum Trioxide nanoparticles in blood and body tissues of male Wistar rats. Materials and Methods: Thirty Wistar rats w...

Data from a recent field campaign in Mexico City are used to evaluate the performance of the EPA Federal Reference Method for monitoring the ambient concentrations of NO2. Measurements of NO2 from standard chemiluminescence monitors equipped with molybdenum oxide converters are compared with those from Tunable Infrared Laser Differential Absorption Spectroscopy (TILDAS) and Differential Optical...

The influence of dietary molybdenum on esophageal carcinogenesis induced by N-methyl-N-benzylnitrosamine (2.5 mg per kg of body weight once a week for 20 wk s.c.) was studied in male F344 rats. The tumor incidence and tumor development in the esophagus were significantly lower in the rats in the high-molybdenum (2 ppm) diet group than in the rats in the low-molybdenum (0.032 ppm) diet group; i....

The ethylene hydrogenation activity is compared for molybdenum oxycarbides, molybdenum carbides and a molybdenum alloy formed by reaction of molybdenum hexacarbonyl with alumina in ultrahigh vacuum using temperature-programmed desorption. It is found that molybdenum oxycarbides are inactive for ethylene hydrogenation. It is shown by forming carbides by reaction between alumina and ethylene that...

The transition element molybdenum needs to be complexed by a special cofactor to gain catalytic activity. Molybdenum is bound to a unique pterin, thus forming the molybdenum cofactor (Moco), which, in different variants, is the active compound at the catalytic site of all molybdenum-containing enzymes in nature, except bacterial molybdenum nitrogenase. The biosynthesis of Moco involves the comp...

In 1938 it was discovered that naturally occurring molybdenum in certain pastures in the United Kingdom was responsible for a severe disease of cattle and sheep (1). The unhealthy pastures were characterized by a molybdenum content of 20 to 1.00 parts per million on the dry basis, as compared with less than 5 p.p.m. in the normal pasture. The experimental production of the disease by administra...

It is conceivable that toxic metals contribute to obesity by influencing various aspects of metabolism, such as by substituting for essential micronutrients and vital metals, or by inducing oxidative stress. Deficiency of the essential metal zinc decreases adiposity in humans and rodent models, whereas deficiencies of chromium, copper, iron, and magnesium increases adiposity. This study utilize...

We recently reported the catalytic generation of hydrogen from water mediated through the in situ reduction of the molybdenum(IV)–oxo complex [(PY5Me2)MoO] 2+ (1; PY5Me2 1⁄4 2,6-bis(1,1-bis(2pyridyl)ethyl)pyridine) at a mercury electrode. To gain further insight into this unique molecular motif for hydrogen production, we have now examined the competence of this complex for the catalytic reduct...