BACKGROUND Evaluation of cancer biomarkers from blood could significantly enable biomarker assessment by providing a relatively non-invasive source of representative tumor material. Circulating Tumor Cells (CTCs) isolated from blood of metastatic cancer patients hold significant promise in this regard. METHODOLOGY/PRINCIPAL FINDINGS Using spiked tumor-cells we evaluated CTC capture on differe...

Because of cellular heterogeneity, the analysis of endogenous molecules from single cells is of significant interest and has major implications. While micromanipulation or cell sorting followed by cell lysis is already used for subsequent molecular examinations, approaches to directly extract the content of living cells remain a challenging but promising alternative to achieving non-destructive...

onion thrips, thrips tabaci lindeman, is a broadly distributed pest that attacks a wide range of crops. to investigate the intra-specific morphometric variation and the genetic diversity of the species in iran, four populations from tobacco plus 18 populations from onion were studied in some 17 provinces of iran. morphological analysis, using principal components and canonical discriminant anal...

genetic diversity among plants sprouted from seven year old clones of mulberry (morus indica var. s36) was studied using molecular markers such as issr and rapd. the clones showed significant variability in sex expression and the sprouting behavior. these changes were appeared after seven years of rigorous pruning and training (pruned once in every 3-4months). genetic diversity analysis reveale...

Background: Canine astrovirus (CAstV) has been considered the primary cause of gastroenteritis in young animals worldwide, while canine vesivirus (CVeV) and canine circovirus (CCiV) are occasionally reported. Aims: This study aimed to investigate the existence and molecular characteristics for these three viruses in Turkey. Methods: Faecal samples from 150 shelter dogs with gastrointestinal pro...

the molecular phylogenetic trees of 42 representative samples of malaysian pangasiid were constructed using cytochrome c oxidase subunit i (coi). the topologies resulting from molecular analyses, maximum parsimony, maximum likelihood, and bayesian inference, revealed the paraphyly of pangasius genus and monophyly of p. nasutus, p. bocourti, p. micronemus, and p. hypopthalmus with high support v...

this study was carried out to determine the protein and carbohydrate molecular structure of sorghum cultivars using fourier transform infrared spectroscopy (ftir) with multivariate molecular spectroscopy analyses. sorghum cultivars included: 1- kimia, 2- sepideh, 3- m2 and 4- m8. protein and carbohydrate molecular functional groups studied included: peak area and height amide i, amide ii, α-hel...