• In this paper we study bias-corrections to the weighted MLE (Dupuis and Morgenthaler, 2002), a robust estimator simply defined through a weighted score function. Indeed, although the WMLE is relatively simple to compute, for most models it is not consistent and hence not very helpful. For example, the model we consider in this paper is the generalized linear latent variable model (GLLVM) prop...

JOHN KNOTT, Popular opposition to the 1834 Poor Law, London and Sydney, Croom Helm, 1986, 8vo, pp. 284, £19.95. Many distinct advances in scholarship have recently converged to re-emphasize the centrality of the Poor Law to the social history of English medicine. It has lately become clear, for the first time, just how extensive were disbursements for sick paupers under the parochial system of ...

Pulmonary emphysema is generally defined anatomically. It follows therefore that pathologists have the best opportunity to diagnose emphysema accurately. Whether they take advantage of this opportunity may be doubted by observers interested in lung disease, and Wyatt, Fischer, and Sweet (1961) have called the usual criteria (gross inspection and palpation of the lung and microscopic examination...

Dirofilariosis is a parasitic disease caused by helminths of the genus Dirofilaria. Climatic changes are considered to be main risk factors for dirofilariosis spreading. In the Slovak Republic, canine subcutaneous dirofilariosis was recorded for the first time in 2005. In 2007 the first coordinated research project started to detect possible endemic infections and to determine their magnitude. ...

BACKGROUND Dirofilaria immitis is a common nematode of the cardiovascular system, which infects carnivores all over the world. The infection is prevalent in dogs, but in cats and human is rare. Dirofilariosis is transmitted by mosquitoes. Cats are accidental hosts and are naturally resistant to the infection, compared to the dogs. Mild infection can cause severe illness in cats and may lead to ...

The present study was conducted to determine the prevalence of canine dirofilariosis in Hatay province, south of Turkey. A total of 269 blood samples were collected from owned dogs in this multi-centre survey between March and July 2006. Blood samples were examined by modified Knott and enzyme-linked immunosorbent assay (ELISA) techniques to detect circulating microfilariae and antigens of Diro...

P. A. Knott,1,2,* T. J. Proctor,1 Kae Nemoto,3 J. A. Dunningham,4 and W. J. Munro2,3 1School of Physics and Astronomy, University of Leeds, Leeds LS2 9JT, United Kingdom 2NTT Basic Research Laboratories, NTT Corporation, 3-1 Morinosato-Wakamiya, Atsugi, Kanagawa 243-0198, Japan 3National Institute of Informatics, 2-1-2 Hitotsubashi, Chiyoda-ku, Tokyo 101-8430, Japan 4Department of Physics and A...