نتایج جستجو برای: mlsb

تعداد نتایج: 144  

Journal: :Journal of bacteriology 1998
T G Oh A R Kwon E C Choi

We cloned the MLSB resistance determinant by PCR from a clinical isolate of Enterococcus faecalis 373, which is induced more strongly by a 16-membered-ring macrolide, tylosin, than by erythromycin. To elucidate the molecular basis of resistance of E. faecalis 373, we analyzed the cloned gene, designated ermAMR, by site-directed mutagenesis and reporter gene assay. Our results showed that an arg...

2014
Harleen Kaur Harbhajan Kaur

The widespread use of Macrolide Lincosamide Streptogramin B (MLSB) antibiotics has led to an increase in the resistant strains. Although Clindamycin is effective against MRSA but its use in the presence of Erythromycin can lead to induction of cross-resistance among members of the MLSB group which could limit the effectiveness of this drug. Furthermore, at times, some strains are also harbored ...

Journal: :jundishapur journal of microbiology 0
asma mesbah elkammoshi faculty of medicine and health sciences, department of medical microbiology and parasitology, universit putra malaysia, serdang, selangor, malaysia hamed ghasemzadeh-moghaddam faculty of medicine and health sciences, department of medical microbiology and parasitology, universit putra malaysia, serdang, selangor, malaysia; faculty of medicine, north khorasan university of medical sciences, bojnurd, ir iran syafinaz amin nordin faculty of medicine and health sciences, department of medical microbiology and parasitology, universit putra malaysia, serdang, selangor, malaysia niazlin mohd taib faculty of medicine and health sciences, department of medical microbiology and parasitology, universit putra malaysia, serdang, selangor, malaysia suresh kumar subbiah faculty of medicine and health sciences, department of medical microbiology and parasitology, universit putra malaysia, serdang, selangor, malaysia vasanthakumari neela faculty of medicine and health sciences, department of medical microbiology and parasitology, universit putra malaysia, serdang, selangor, malaysia

background antibiotic resistance among staphylococcus aureus is of great concern worldwide. this resistance is further complicated by the ability of s. aureus to confer cross-resistance to other antibiotics due to the presence of resistance genes, such as erythromycin resistance methylase (erm) genes, which render the bacterium resistant to macrolide-lincosamide-streptogramin b (mlsb) antibioti...

Journal: :Healthcare in low-resource settings 2023

Against the backdrop of ever-changing Staphylococcal resistance pattern, clindamycin remains a viable therapeutic alternative Variation Clindamycin drug patterns with geographic area make inducible testing imperative for all staphylococcal isolates to avoid failure. This was prospective study conducted over period 1.5 years from January 2021 until June 2022. Prevalence different MLSB Phenotypes...

ژورنال: :مجله دانشکده پزشکی اصفهان 0
مهتاب السادات موسوی islamic azad university falavarjan branch وجیهه کرباسی زاده

مقدمه با افزایش مقاومت آنتی بیوتیکی در میان عوامل ایجاد کننده عفونت های بیمارستانی درمان چنین عفونت هایی با مشکل روبرو شده است. استافیلوکوکوس اپیدرمیدیس به عنوان یکی از شایع ترین دلایل عفونت های بیمارستانی شناخته شده است. این مطالعه، با هدف تعیین فراوانی مقاومت به آنتی بیوتیک های ماکرولید، لینکوزآمید و استرپتوگرامین mlsb)) در جدایه های بالینی استافیلوکوکوس اپیدرمیدیس مقاوم به متی سیلین (mrse) ا...

2003

infections (RTIs) continues to be an international challenge; RTIs are associated with considerable morbidity and mortality in both developed and developing countries. Globally, lower RTIs accounted for 4.3 million premature deaths in 1990.1 A major barrier to the confident prescribing of empiric therapies for RTIs is the increasing resistance worldwide among respiratory tract pathogens to exis...

اشجع اردلان, آذین, باغبانی ارانی, فهیمه, فتاحی راد, آزاد, کشاورزی, فاطمه,

زمینه و اهداف: افزایش مقاومت دارویی به ماکرولیدها احتمالاً بدلیل مصرف بی رویه و نا بجای این آنتی بیوتیک می باشد. هدف از مطالعه حاضر، بررسی مقاومت به ماکرولیدها در ایزوله های استرپتوکوک بتا همولیتیک گروهA جدا شده از نمونه های بالینی حامل ژن mef و مقایسه فنوتیپ و ژنوتیپ آن ها و همچنین بررسی میزان فراوانی این باکتری در جامعه مورد مطالعه بود. مواد و روش ها: چهل نمونه استرپتوکوک پیوژنز بتا همولیتیک گ...

2009
Nicholas J. Tobias Torsten Seemann Sacha J. Pidot Jessica L. Porter Laurent Marsollier Estelle Marion Franck Letournel Tasnim Zakir Joseph Azuolas John R. Wallace Hui Hong John K. Davies Benjamin P. Howden Paul D. R. Johnson Grant A. Jenkin Timothy P. Stinear

Mycolactone A/B is a lipophilic macrocyclic polyketide that is the primary virulence factor produced by Mycobacterium ulcerans, a human pathogen and the causative agent of Buruli ulcer. In M. ulcerans strain Agy99 the mycolactone polyketide synthase (PKS) locus spans a 120 kb region of a 174 kb megaplasmid. Here we have identified promoter regions of this PKS locus using GFP reporter assays, in...

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