Miktoarm star triblock copolymers mu-[poly(ethylethylene)][poly(ethylene oxide)][poly(perfluoropropylene oxide)] self-assemble in dilute aqueous solution to give multicompartment micelles with the cores consisting of discrete poly(ethylethylene) and poly(perfluoropropylene oxide) domains. Tetrahydrofuran is a selective solvent for both the poly(ethylethylene) and poly(ethylene oxide) blocks, an...

Turbidimetry, dynamic light scattering, and capillary electrophoresis were used to study the complexation of polydiallyldimethylammonium chloride (PDADMAC) with mixed micelles of sodium dodecyl sulfate (SDS) and dodecanol ethoxylates (C12En). The effect of EO chain length and its distribution was examined using various combinations of C12En (n = 4, 6, 8, 12). The results show that the onset of ...

Two types of microemulsion reaction systems: simple and mixed reverse micelles have been investigated as potential bioreactors for a transglycosylation reaction catalyzed by three microbial b-galactosidases: fungal Aspergillus oryzae, yeast Kluyveromyces marxianus and bacterial Escherichia coli b-galactosidase. Several issues such as: the effect of the degree of hydration on the total enzyme ac...

Sodium dodecyl sulfate (SDS)-poly(propylene oxide) methacrylate (PPOMA) (of molecular weight M(w) = 434 g x mol(-1)) mixtures have been studied using conductimetry, static light scattering, fluorescence spectroscopy, and 1H NMR. It has been shown that SDS and PPOMA form mixed micelles, and SDS and PPOMA aggregation numbers, N(ag SDS) and N(ag PPOMA), have been determined. Total aggregation numb...

Androst-3β,5α,6β-triol (Triol) is a promising neuroprotective agent, but its poor solubility restricts its development into parenteral preparations. In this study, Triol is significantly solubilized by bile salt/phosphatidylcholine mixed micelles (BS/PC-MM). All BS/PC-MM systems are tested to remarkably improve the drug solubility with various stabilities after drug loading. Among them, the sod...

The interaction between pyrene-labeled poly(acrylamido)-2-methylpropane sulfonate) (PyPAMPS) and mixed micelles of n-dodecylhexaoxyethylene glycol monoether/n-hexadecyltrimethylammonium chloride (C12E6/CTAC) was studied by turbidimetry, quasielastic light scattering (QELS), fluorescence quenching, and UV spectroscopy. The present report focuses on the effect of the pyrene label on the polymer-m...

Mixed lipid micelles were isolated from rat bile on taurocholate-equilibrated Sephadex G100 and G200 columns (5-60 mM) to study relationships between lipids and other constituents of bile. Phospholipid, cholesterol, and a bile salt peak co-eluted as mixed micelles at all taurocholate concentrations. The micellar radius, derived from the elution profile, increased progressively from approximatel...

Mixed micelles of l,2-diheptanoyl-sn-grycero-3-phosphocholine (DHPC) with ionic detergents were prepared to develop well characterized substrates for the study of lipolytic enzymes. The aggregates that formed on mixing DHPC with the anionic surfactant sodium dodecyl sulfate (SDS) and with the positively charged dodecyl trimethylammonium bromide (DTAB) were investigated using time-resolved fluor...

By analysis of experimental data, a quantitative theoretical interpretation of the solubility limit of medium- and long-chain fatty alcohols in micellar solutions of water-soluble surfactants is presented. A general picture of the phase behavior of the investigated systems is given in the form of phase diagrams. The limited solubility of the fatty alcohols in the micelles of conventional surfac...