BACKGROUND Although substance misuse is a key risk factor in suicide, relatively little is known about the relationship between lifetime misuse and misuse at the time of suicide. AIMS To examine the relationship between substance misuse and subsequent suicide. METHOD Linkage of coroners' reports to primary care records for 403 suicides occurring over 2 years. RESULTS With alcohol misuse, ...

OBJECTIVE Social role transitions have been linked to changes in substance use and misuse during young adulthood. This study examined how commonly observed pathways to adulthood, defined by education, employment, marriage, and parenthood, were associated with alcohol, tobacco, and marijuana misuse from ages 18 to 33. METHOD Data came from a longitudinal panel of 412 men and 396 women recruite...

The aim of the study was to investigate trajectories of social functioning in young people with first-episode psychosis (FEP) with and without cannabis misuse using a secondary analysis of data from the Episode-II trial. Forty-two young people with FEP and comorbid cannabis use disorder were compared with 39 young people with FEP but without a cannabis use disorder. Social functioning was asses...

Patients with chronic pain and depression are more likely to develop opioid abuse compared to patients without depression. It is not known if this association differs by pain location. We compared the strength of association between depression and opioid misuse in patients with chronic low back pain (CLBP) vs. chronic pain of other location (CPOL). Chart abstracted data was obtained from 166 pa...

There are several methods for the derivation and analysis of detailed non-functional requirements. They often are designed for a special application, like misuse cases for top-down derivation of requirements detailing the quality attribute “security”, or ATAM for evaluating given architectural alternatives. In this work, we apply misuse cases to any other quality attribute (e.g. usability, effi...