Objective We compared the expression levels of Müllerian inhibiting substance (MIS)/anti-Müllerian hormone type II receptor (AMHRII) in uterine myoma and adenomyosis to evaluate the possibility of using MIS/anti-Müllerian hormone (AMH) as a biological regulator or therapeutic agent in patients with uterine leiomyoma and adenomyosis. Methods We studied normal uterine myometrium, leiomyoma, end...

A somewhat controversial but continuing trend among large divisionalized corporations is to centralize the provision of information system services in the MIS department. The objectives of centralizing all or most MIS activities are to. obtain economies of scale in the acquisition of computer hardware and to eliminate duplicate system development 191. The centralization of MIS functions, howeve...

Misonidazole (MIS) is a hypoxic cell radiosensitizer currently undergoing Phase III clinical trials in the treatment of cancer by radiation. It is also a cytotoxic agent with specificity toward hypoxic cells, and consequently has a tumoricidal effect in laboratory animals. This tumoricidal effect has not been clinically applicable, in part because the initial resistance to the cytotoxic action ...

Müllerian inhibiting substance (MIS) is a sexually dimorphic gonadal hormone with proven efficacy in the evaluation of boys with cryptorchidism and children with intersex conditions. We examined the role of MIS determination in the evaluation of 65 phenotypic females with mild virilization. Among the 28 subjects with MIS values elevated above the normal female range, all had abnormal gonadal ti...

BACKGROUND This study investigates the feasibility of performing advanced minimally invasive surgery (MIS) in a nonspecialized practice environment. METHODS We conducted a cross-sectional survey of all community general surgeons currently practising in Ontario. RESULTS Few community surgeons perform a high volume (> 10 procedures per yr) of advanced MIS. Most (70%) believe it is important t...

The critical success factors (CSFs) of MIS managers have been previously studied by two authors using dramatically different approaches and producing different taxonomies. This study integrates these two taxonomies by mapping corresponding items and developing an expanded framework based on the originals. The new framework is used forMIS managers' ranking of CSFs by their level of importance. T...

Given a finite set V , and integers k ≥ 1 and r ≥ 0, denote by A(k, r) the class of hypergraphs A ⊆ 2 with (k, r)-bounded intersections, i.e. in which the intersection of any k distinct hyperedges has size at most r. We consider the problem MIS(A, I): given a hypergraph A and a subfamily I ⊆ I(A), of its maximal independent sets (MIS) I(A), either extend this subfamily by constructing a new MIS...

This study aimed to analyze expression of Müllerian inhibiting substance type II receptor (MISRII) protein and mRNA in cervical neoplasia, to demonstrate the growth inhibition of cervical cancer cells by administration of highly purified recombinant human Müllerian inhibiting substance (MIS) and, furthermore, to evaluate the clinical significance ...

Misonidazole (MIS) is a hypoxic cell radiosensitizer currently undergoing Phase III clinical trials in the treatment of cancer by radiation. It is also a cytotoxic agent with specificity toward hypoxic cells, and consequently has a tumoricidal effect in laboratory animals. This tumoricidal effect has not been clini cally applicable, in part because the initial resistance to the cytotoxic action...

Múllerian Inhibiting Substance (MIS) is a testicular hormone that promotes involution of the Múllerian duct during embryogenesis. The Múllerian duct gives rise to adult female reproductive ducts including the fallopian tubes, uterus, and upper vagina. Thus, testicular MIS ensures the regression of female sex organ primordia. Partially purified bovine MIS was reported to inhibit proliferation of...