This scientific review presents the processes of regulation miRNA content. To write article, information was searched using Scopus, Web Science, MedLine, PubMed, Google Scholar, EMBASE, Global Health, The Cochrane Library, CyberLeninka databases. article characteristics microRNA editing and tailing, which regulate content through transcription control. It is emphasized that most important mecha...

although more than 98% of the human genome is transcribed, most of these transcripts are not translated into proteins. rather, they are considered as non-coding rnas. micrornas (mirnas) are very short non-coding rnas approximately 22 nucleotides in length which regulate many key processes of cells such as growth, proliferation, differentiation, cell cycle, apoptosis (programmed cell death) and ...

conclusions our results revealed the possible crucial genes and mirnas involved in the initiation and progression of hcc cells infected with hcv. results based on the topological analysis of mirna-hubgene network, we identified the key hub mirnas. in order to identify the most important common sub-network, we aligned two ppi networks using netal tool. the c-jun gene was identified as the most i...

MicroRNAs (miRNA) are a class of short noncoding RNA that play important roles in controlling gene expression. Many miRNAs have been identified as being regulators bone cell function, thus affecting the remodeling processes. In addition to expressed specific tissues and exerting intracellular effects, can enter blood where they be taken up by other tissues. These circulating (c-miRNA) also clin...

Epilepsy is a common and serious neurological disorder characterised by recurrent spontaneous seizures. Frontline pharmacotherapy includes small-molecule antiseizure drugs that typically target ion channels neurotransmitter systems, but these fail in 30% of patients do not prevent either the development or progression epilepsy. An emerging therapeutic microRNA (miRNA), small noncoding RNAs nega...

Long non-coding RNAs (lncRNAs) play a multifaceted role in transcriptional regulation, and the potential molecular regulatory mechanisms of lncRNAs lncRNA–miRNA–mRNA networks body color formation are great significance for its selective breeding. Therefore, lncRNA-miRNA-mRNA ceRNA network red- black-colored Plectropomus leopardus were identified analyzed. Sequencing analyses 167 differentially ...