Abstract Background Pericoronary adipose tissue (PCAT) plays a key role in the pathogenesis of atherosclerosis. PCAT is source microRNAs (miRs) that acts as messengers for intercellular communication. In this study, we investigated whether surrounding coronary occlusive atherosclerotic lesions shows specific miR expression patterns compared to plaque-free segments. Purpose To evaluate miRs are ...

in the recent years deregulation for micrornas expression pattern have emerged as a possible molecular factor for carcinogenesis. it has been reported that the expression of mir-9 was down-regulated in human gastric adenocarcinoma. to figure out the molecular mechanism of this down regulation, the methylation status in promoters of mir-9 family loci were compared in the human gastric adenocarci...

Purpose: To investigate the effects of circ_0001953/miR-186 on human retinal vascular endothelial cell (HRVEC) injury evoked by high glucose. Methods: A model (HG group) was established using glucose-treated HRVECs, while untreated HRVECs were used as control group (Con group). The levels endothelin-1 (ET-1), ICAM-1 and IL-6 evaluated ELISA content malondialdehyde (MDA) superoxide dismutase (SO...

Mytilus coruscus is a significant economic species in China’s eastern coastal areas. As dioecious species, it lacks secondary sexual characteristics, which makes difficult for selective breeding. However, limited research carried out on the genetic data regarding reproductive development and gender differentiation. In current study, de novo transcriptome sequencing analyses were used to detect ...

Introduction/Background Cervical cancer (CC) is one of the most common types and fourth leading cause cancer-related deaths in women. carcinogenesis multistep process cervical dysplasia development progression. Correct diagnostic effective therapy presents an important approach to reduce CC morbidity mortality. MicroRNAs epithelium cells are considered as promising markers dysplasia. M...

MicroRNA are short and non-coding RNA, 18-25 nucleotides in length. They produced at the early stage of viral infection. The roles played by cellular miRNAs miRNA-mediated gene-silencing COVID-19 epidemic period is critical order to develop novel therapeutics. We analyzed SARS-CoV-2 Surface Glycoprotein (S) nucleotide sequence originating from India as well Iran, Australia, Germany, Italy, Russ...