Using molecular modeling approach, potential antibacterial agents with triazole core were proposed. A moderate to weak level of antibacterial activity in most of the compounds have been observed, with best minimal inhibitory concentration (MIC) value of 0.003 mg/mL, as shown by the 15 against S. epidermidis. Studied compounds were also submitted to the antifungal assay. The best antifungal acti...

Objective The standard of hygiene in daily life and hospitals can be increased by the use of new antimicrobial fibers, which diminish the danger of pathogenic bacteria. In this study, the antimicrobial effect of special fibers on some staphylococcus isolates was investigated. Materials and Methods The antimicrobial effect of special type of fibers produced in Isfahan Poly Acryl Plant on thre...

Microcin J25 (MccJ25) is a small ribosomally synthesized antimicrobial peptide that is produced by Enterobacteriacea family especially E.coli. The present study focuses on preparation and evaluation of in vitro antimicrobial and biological properties of a new peptide derived from MccJ25. We prepared a MccJ25-derived peptide containing 14 amino acids and a single intra-molecular disulfide bond a...

in this study, invitro evaluation of some iranian plants against staphylococcus aureus isolation of urinary tract infection by microtiterplate method. all 12 strains of staphylococcus aureus isolated from urine culture of hospitalized patients during the years 2012- 2013. minimum inhibitory concentration (mic) of plant extract and essential oilagainst bacteria were determined using micro diluti...

Biofilm production is an important mechanism that allows microbes to escape host defences and antimicrobial therapy. Vancomycin has been used largely for the treatment of methicillin-resistant staphylococcal infections. Here, we determined the minimal inhibitory concentration (MIC) and minimal biofilm eradication concentration (MBEC) for 82 Staphylococcus species isolated from central venous ca...

The anti-Listeria monocytogenes activity of four essential oils (EOs) (Salvia officinalis, Citrus limon, Mentha piperita and Thymus vulgaris) bacteriocin bacLP17, added alone or in mixture active edible coatings, was determined artificially contaminated shrimps. minimal inhibitory concentration (MIC) values the EOs were against NCTC 10888 strain L. by using broth microdilution method. checkerbo...

Methicillin-resistant Staphylococcus aureus (MRSA) infection is a serious clinical problem worldwide. The aim of the present study was to examine the antimicrobial activity of oxyresveratrol (ORV) against MRSA. The antimicrobial activity of ORV was evaluated against three strains of MRSA and one methicillin-susceptible S. aureus (MSSA) strain using a minimal inhibitory concentration (MIC) assay...

Due to the growing number of outbreaks of infection in hospital and nurseries, it becomes essential to set up a sanitation program that indicates that the appropriate chemical agent was chosen for application in the most effective way. Validating the effectiveness of decontamination and disinfection is an important and often challenging task. In order to study and compare the behavior of select...

materials and methods one hundred ssis specimens were obtained by needle aspiration from purulent material in depth of infected site. these specimens were cultured and incubated in both aerobic and anaerobic condition. for detection of antibiotic susceptibility pattern in aerobic and anaerobic bacteria, we used disk diffusion, agar dilution, and e-test methods. results a total of 194 bacterial ...