The goal of the research reported in this thesis is to contribute to early and accurate detection of dementia. Early detection of dementia is essential to maximising the effectiveness of treatment against memory loss. This goal is pursued by interpreting the Mini-Mental State Examination (MMSE) in novel ways. The MMSE is the most widely used screening tool for dementia, it is a questionnaire of...

OBJECTIVE To review administration of the Standardized Mini-Mental State Examination (SMMSE) for dementia and depression and to evaluate how well it interprets older people's cognitive function. QUALITY OF EVIDENCE Literature from January 1990 to December 1999 was searched via MEDLINE using the MeSH headings Alzheimer Disease, Vascular Dementia, Lewy Bodies, and Depression. Several studies ha...

Materials and methods The study included two groups. The first consisted of 20 patients with Parkinson’s disease, who were outpatients in the Movement Disorder Clinic and the Memory Clinic of the Neurological Clinic of two public health general hospitals and a university hospital. The second consisted of 20 healthy controls. The two groups were matched for age and education. Patients with Parki...

OBJECTIVE To assess the value of brainstem auditory evoked potentials and event related evoked potential (3rd positive component of evoked related potentials with latency of 300 millisecond, in evaluating cognitive dysfunction in patients with chronic respiratory failure. METHODS Thirty-two patients with chronic obstructive pulmonary disease and respiratory failure of mild to moderate severit...

Mini-Mental State Examination (MMSE) is used as a diagnostic test for dementia to screen patient’s cognitive assessment and disease severity. However, these examinations are often inaccurate unreliable either due human error or patients’ physical disability correctly interpret the questions well motor deficit. Erroneous data may lead wrong of specific patient. Therefore, other clinical factors ...