Epilepsy and migraine are common diseases of the nervous system and share genetic and pathophysiological mechanisms. Familial hemiplegic migraine is an autosomal dominant disease. It is often used as a model of migraine. Four genes often contain one or more mutations in both epilepsy and hemiplegic migraine patients (ie, CACNA1A, ATP1A2, SCN1A, and PRRT2). A better understanding of the shared g...

BACKGROUND An association between restless legs syndrome and migraine has been reported recently. The clinical correlates and impact of comorbidity of restless legs syndrome (RLS) are not fully described in patients with migraine. OBJECTIVES To investigate the frequency of RLS among different primary headache disorders, and its impact and clinical correlates in migraine patients. METHODS Co...

Headache during pregnancy is frequent and challenging. A secondary headache diagnosed in one third of women, most causes are vascular infectious disorders. Anamnestic clinical features must be investigated, brain imaging often required. Primary headaches commonly modified pregnancy. Migraine mainly improved this context, especially migraine without aura. Particular cautions about treatment appl...

Migraine frequently co-occurs with depression. Using a large sample of Australian twin pairs, we aimed to characterize the extent to which shared genetic factors underlie these two disorders. Migraine was classified using three diagnostic measures, including self-reported migraine, the ID migraine™ screening tool, or migraine without aura (MO) and migraine with aura (MA) based on International ...

OBJECTIVE The importance of psychiatric comorbidity in migraine has long been recognized. There is a growing body of evidence that these psychiatric comorbidities share diverse epidemiological properties, pathophysiological mechanisms, and treatment response. The prevalence of psychiatric comorbidities is high in patients with medication-overuse headache (MOH). METHODS To understand the chara...

BACKGROUND Comprehensive diets do not require the exclusion of a specific provocative food or ingredient, but regulate the quantities of core components of foods such as vitamins, ions, proteins, carbohydrates, and fats. OBJECTIVES To review the evidence supporting the use of comprehensive diets in the prevention of migraine and other headache disorders and to discuss the mechanisms through w...

This paper presents diagnostic criteria for vestibular migraine, jointly formulated by the Committee for Classification of Vestibular Disorders of the Bárány Society and the Migraine Classification Subcommittee of the International Headache Society (IHS). The classification includes vestibular migraine and probable vestibular migraine. Vestibular migraine will appear in an appendix of the third...

A significant body of literature exists demonstrating a relationship between migraine disorders and dizziness. In the characterizations of the migraine-associated dizziness, the signs and symptoms show overlap with those characterizing Meniere's disease. There has been literature, beginning with Ménière himself, suggesting a relationship between Ménière's disease and migraine-associated dizzine...

The development of the diagnostic and classification criteria for headache disorders from the International Headache Society has benefited not only practicing headache specialists but also epidemiologists. We now have a wealth of data from international epidemiological studies on the prevalence and cost of migraine and other headache disorders. The data reveal the significant impact these disor...