Department of Clinical Pharmacy and Biopharmaceutics, Mie University Graduate School of Medicine (K.I., Y.H., T.I., M.O.), Tsu, Mie 514-8507, Japan Department of Pharmacy, Mie University Hospital (K.I., T.E., Y.M., T.I., M.O.), Tsu, Mie 514-8507, Japan Faculty of Pharmaceutical Sciences, Suzuka University of Medical Science, Suzuka (C.K.), Mie 513-8670, Japan Department of Pulmonary and Critica...

BACKGROUND Minimally invasive esophagectomy (MIE) is increasingly used for the treatment of esophageal cancer. However, the ideal approach of MIE is not yet standardized. We explore the ideal approach of MIE according to the location of the tumor and compare the clinical outcomes between patients with cancer arising in the upper third of the esophagus and those with tumors involving the middle ...

BACKGROUND The advantage of neoadjuvant chemotherapy (NAC) followed by open esophagectomy for treatment of esophageal squamous cell carcinoma has been widely recognized. However, the safety and feasibility of NAC for patients receiving minimally invasive esophagectomy (MIE) remain controversial. The purpose of this study was to evaluate the potential impact of prior neoadjuvant chemotherapy on ...

For the case of a simple face-centered-cubic photonic crystal of homogeneous dielectric spheres, we examine to what extent single-sphere Mie resonance frequencies are related to band gaps and whether the width of a gap can be enlarged due to nearby resonances. Contrary to some suggestions, no spectacular effects may be expected. When the dielectric constant of the spheres εs is greater than the...

Minimally invasive esophagectomy (MIE) by thoracoscopy after neoadjuvant therapy results in significant short-term advantages such as a lower incidence of pulmonary infections and a better quality of life (QoL) with the same completeness of resection. After 1 year, a better QoL is still observed for MIE in comparison with the open approach, while having the same survival. Seven issues about imp...

The Adverse Outcome Pathway (AOP) paradigm details the existing knowledge that links the initial interaction between a chemical and a biological system, termed the molecular initiating event (MIE), through a series of intermediate events, to an adverse effect. An important example of a well-defined MIE is the formation of a covalent bond between a biological nucleophile and an electrophilic com...

A Mie-Bruggeman spectral model is presented which predicts the orientationally averaged, infrared spectra of individual mixed-composition particles or the average spectrum of collections of such particles. The model uses parameters extracted from sets of individual particle spectra of pure materials known to be in subject mixtures. The spectra of both calibrants and subject particles were recor...

Lorenz-Mie resonances produced by small spheres are analyzed as a function of their size and optical properties (epsi > or < 0, mu > or < 0). New generalized (mu not equal to 1) approximate and compact expressions of the first four Lorenz-Mie coefficients (a1, b1, a2, and b2) are calculated. With these expressions and for small particles with various values of epsi and mu, the extinction cross ...