Targeted alpha therapy is an emerging alternative for palliative of a wide range tumor types. Data from preclinicaland clinical research demonstrates high potential the selective killing cells and minimal toxicity to surroundinghealthy tissues. This article summarizes developmental stages alpha-targeted benchtop commercialization.It discusses fundamental properties, production pathways, microdo...

Reverse-biased silicon p-n junction arrays using Silicon-On-Insulator technology have been proposed as microdosimeters. The performance of such detectors in boron neutron capture therapy (BNCT) is discussed. This work provides the first reported measurements using boron-coated silicon diode arrays as microdosimeters in BNCT. Results are in good agreement with measurements with gas proportional ...

The objective of microdosimetry was, and still is, to identify physical descriptions of the initial physical processes of ionising radiation interacting with biological matter which correlate with observed radiobiological effects with a view to improve the understanding of radiobiological mechanisms and effects. The introduction of therapy with particles starting with fast neutrons followed by ...