background: there are reports about the increase of severity of infections in patients receiving morphine. therefore this study was aimed to evaluate the effect of morphine on phagocytic activity of peritoneal phagocytes of mice. methods: fifty six female balb/c mice, 6-8 weeks old and 28±2 gram weight, were divided into two groups. the case group received 20, 40, 60 and 80 mg/kg morphine on fi...

background: in recent years, immunocompromised patients are at high risk for the development of invasive aspergillosis. due to the increase of antimicrobial resistance, natural agents with medicinal and immunomodulatory effects has gained more attention. honey is a natural substance with documented antimicrobial, anti-inflamatory and wound healing effects. objectives: the purpose of this study ...

Noyes, Howard E. (Walter Reed Army Institute of Research, Washington, D.C.), William L. Pritchard, Floyd B. Brinkley, and Janice A. Mendelson. Analyses of wound exudates for clostridial toxins. J. Bacteriol. 87:623-629. 1964.-Earlier studies indicated that death of goats with traumatic wounds of the hindquarter could be related to the number of clostridia in the wounds, and that toxicity of wou...

Willoughby, Donald S. (University of Minnesota, Minneapolis), and Dennis W. Watson. Host-parasite relationships among group A streptococci. II. Influence of sex on the susceptibility of inbred mice toward streptococcal infection. J. Bacteriol. 87:1457-1461. 1964-BALB/Sy mice showed marked sex differences in susceptibility to a strain of Streptococcus pyogenes type 18. Castration of the highly s...

conclusions our results demonstrated the promising prophylactic and therapeutic effects of propranolol against t. gondii infection. propranolol also increases the efficacy of pyrimethamine in combination therapies. results in the pre-treatment group, results showed that propranolol at 2 and 3 mg/kg combined with pyrimethamine was more effective in inhibiting growth of tachyzoites (86% and 98%, ...

Inhibition of Concanavalin A-induced lymphocyte proliferation was used to monitor the partial purification and characterization of suppressor molecules from microfilariae of Brugia malayi. Suppressor activity was present in high molecular weight fractions of microfilarial extracts (Mr greater than 50 kd on SDS-PAGE) and was protease-sensitive but resisted treatment with sodium periodate, indica...

Sterile peritoneal exudates produced in rabbits injected with 1% glycogen contain a phospholipase A activity in a cell-free supernatant fraction that hydrolyzed a synthetic phospholipid (1,2-diacyl-sn-glycero-3-phosphoethanolamine) and phospholipids of autoclaved Escherichza coli. This phospholipase activity (phosphatidylacylhydrolase EC 3.1.1.4) exhibited an apparent bimodal pH optimum (pH 6.0...