power stations produce a range of magnetic fields more than 20 mt which are harmful to those working or living around them. several investigators have reported an increased health risk due to exposure to electric and magnetic fields (emf) at 50 and 60 hz. several studies have been reported especially with increased tumor incidence, effects on reproduction and development, and neural and behavio...

Miller Fisher syndrome (MFS) is an acute demyelinating disorder that is considered a cranial nerve variant of Guillain-Barré syndrome (GBS). The pathophysiological process behind MFS is immune-mediated nerve damage but there is some debate with regards to whether this is primarily due to central nervous system (CNS) or peripheral nerve involvement. Headache has been described more frequently in...

Marfan syndrome (MFS) is an autosomal dominant heterogeneous disorder of connective tissue characterized by the early development of thoracic aneurysms/dissections, together with defects of the ocular and skeletal systems. Loss-of-function mutations in fibrillin-1 (FBN1) encoded by the gene, FBN1 (MFS‑1), and in the transforming growth factor β receptor 2 (TGFBR2) gene, TGFBR2 (MFS‑2), are majo...

Marfan syndrome (MFS), the founding member of connective tissue disorder, is an autosomal dominant disease; it is caused by a deficiency of the microfibrillar protein fibrillin-1 (FBN1) and characterized by involvement of three main systems; skeletal, ocular, and cardiovascular. More than one thousand mutations in FBN1 gene on chromosome 15 were found to cause MFS. Nephrotic syndrome (NS) had b...

Marfan syndrome (MFS) is a genetic disorder which is inherited by autosomal dominant traits. In MFS, lens displacement and cardiovascular involvement are important causes of morbidity and mortality in the clinical course of the disease. In this case study, the ocular involvement in a family with severe penetration of MFS is reported. Twelve members of a family (father, two daughters, three sons...

Marfan syndrome (MFS) is an autosomal-dominant disorder of connective tissue caused by mutations in the fibrillin-1 (FBN1) gene. Mortality is often due to aortic dissection and rupture. We investigated the structural and functional properties of the heart and aorta in a [Fbn1C1039G/+] MFS mouse using high-resolution ultrasound (echo) and optical coherence tomography (OCT). Echo was performed on...

Oral tongue squamous cell carcinoma (OTSCC) has a high mortality rate and the incidence is rising worldwide. Despite advances in treatment, the disease lacks specific prognostic markers and treatment modality. The spreading of OTSCC is dependent on the tumor microenvironment and involves tumor-associated macrophages (TAMs). Although the presence of TAMs is associated with poor prognosis in OTSC...

OBJECTIVE To report outcomes in a recent series of pregnancies in women with Marfan syndrome (MFS). DESIGN Retrospective case note review. SETTING Tertiary referral unit (Chelsea and Westminster and Royal Brompton Hospitals). SAMPLE Twenty-nine pregnancies in 21 women with MFS between 1995 and 2010. METHODS Multidisciplinary review of case records. MAIN OUTCOME MEASURES Maternal and n...

background: multidimensional fatigue syndrome (mfs) is referred to as extreme inability accompanied by decline in physical functional capacity and impairment of intellectual function, such as loss of concentration. elderly people are more prone to mfs comparing to other age groups. it is expected that adequacy of dialysis affect the process of mfs among patients under dialysis. the purpose of t...

BACKGROUND Routine staining procedures often pose a problem in differentiating a mitotic cell from an apoptotic cell, deteriorating the reliability of histology grading. Although various new methods have been recommended for identifying mitotic figures (MFs) in tissues, the time factor and cost makes them less feasible. Thus, an attempt was made to evaluate the efficacy of crystal violet and Fe...