The reaction of [4-g1utamic acidjdeamlnc-l-carba-oxytocin (lb) with diazoalkanes yielded the corresponding methyl ester Ie and ethyl ester ld. Alternatively, the methyl ester was prepared by means of carbodiimide or thionyl chloride, or by treating the caesium salt of compound Ib with methyl iodide. [2-0~Methyltyrosine, 4-glutamic acid methyl esterjdeamino-f-carba-oxytccin (liz) was also synthe...

Fatty acid methyl esters, which are used as biodiesel, can be produced by esterification of fatty acids in supercritical methanol. However, a reverse reaction, esters hydrolyzed to regenerate due the presence water, is making it difficult reduce content sufficiently. In this study, oleic was treated methanol at 310 °C/20 MPa with flow-type reactor adding formate improve yield ester. As result, ...

Bergenia ciliata is a weed of hilly areas Pakistan that generally grows in rock crevices. In the present study, flowers this weeds were collected from Murree. The dried extracted methanol and subjected to GC-MS analysis showed 7 compounds it. predominant compound was hexanedioic acid, bis(2-ethylhexyl) ester (48.88%) followed by γ-sitosterol (22.56%). Moderately occurring cyclohexane, 1,3,5-tri...

background: the presence of nitric oxide (no) in the cuneiform nucleus (cnf) has been previously shown. in this study, ng-nitro-l-arginine methyl ester (l-name) (an inhibitor of no synthase), l-arginine (l-arg) (a precursor of no), and sodium nitroprusside (snp) (a donor of no) were microinjected into the cnf and cardiovascular responses were investigated. methods: seventy male rats were divide...

Chemical investigation of the fungus Penicillium sp. SCSIO Ind16F01 derived from deep-sea sediment sample afforded a new xanthone, 3,8-dihydroxy-2-methyl-9-oxoxanthene-4-carboxylic acid methyl ester (1) and a new chromone, coniochaetone J (2), together with three known xanthones, 8-hydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ester (3), 7,8-dihydroxy-6-methyl-9-oxo-9H-xanthene-1-...

A thorough investigation of the mode of action of Aspergillus niger (4M-147) pectin lyase A (PLA) on differently C(6)-substituted oligogalacturonides is described. PLA appeared to be very specific for fully methyl-esterified oligogalacturonides: removal of the methyl-ester or changing the type of ester (ethyl esterification) or transamidation resulted in (almost) complete loss of conversion. Th...

Plants of the genus Taraxacum Wigg., have long been used as medicinal herbs. A phytochemical investigation of the aerial parts of Taraxacum bessarabicum (Hornem.) Hand.-Mazz. subsp. bessarabicum (Hornem.) Hand.-Mazz. (Asteraceae) yielded two coumarins [esculetin (1), cichoriin (2)], three flavonoids [ luteolin (3), luteolin 7-O-β-D-glucoside (4), gossypetin (5)] and six phenolic acids and their...

In the enanti-opure crystal of the title compound, C(4)H(10)NO(3) (+)·Cl(-), inter-molecular O-H⋯Cl and N-H⋯Cl hydrogen bonds link the mol-ecules into layers parallel to (001).

This study evaluated the effects of progressive nitric oxide (NO) inhibition in the regulation of systemic and regional hemodynamics and renal function in anesthetized dogs. The N(G)-nitro-L-arginine methyl ester group (n = 9) received progressive doses of 0.1, 1, 10, and 50 microg. kg(-1). min(-1). Renal (RBF), mesenteric (MBF), iliac (IBF) blood flows, mean arterial pressure (MAP), pulmonary ...