نتایج جستجو برای: methoxsalen
تعداد نتایج: 439 فیلتر نتایج به سال:
The natural occurrence of biologically active furanocoumarins in common vegetables is an area of increasing interest with respect to human health. In this study, an efficient, rugged, and sensitive liquid chromatographic method with ultraviolet photodiode array detection was developed for the estimation of 5 biologically active furanocoumarins (psoralen, bergapten, xanthotoxin, trioxsalen, and ...
A series of novel imperatorin derivatives were synthesized from commercially available xanthotoxin. The in vitro pharmacological evaluation indicated that all of the compounds possessed potent vasodilatory activity. Among them, compounds (5b), (5d) and (5e) exhibited higher vasdilatory activity (with EC(50) values of 0.68 µM, 0.59 µM and 0.49 µM, respectively) than imperatorin (EC(50) = 1.12 µM...
BACKGROUND Few studies have directly compared the clinical efficacy of psoralen plus ultraviolet A (PUVA) vs. biologics in the treatment of psoriasis. OBJECTIVES To compare the clinical efficacy of PUVA and biologic therapies for psoriasis under daily life conditions. METHODS Data from a psoriasis registry (http://www.psoriasis-therapieregister.at) of 172 adult patients with moderate to sev...
To the Editor: We report the case of an 80-yearold man with localized scleroderma, treated successfully with PUVA therapy. The patient came to our office with progressive hardening of his abdominal skin. Clinical examination (Fig. 1) showed a large (25 cm in diameter) slightly erythematous plaque that could not be pinched and made it difficult for the patient to bend down. The lesion margins we...
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