The current paper presents an introduction to a special issue focusing on mathematical flexibility, which is important aspect of thinking and cherished, but capricious, outcome mathematics education. Mathematical flexibility involves the flexible, creative, meaningful, innovative use concepts, relations, representations, strategies. In this we discus...

In decision making regarding optimal resource allocation to safeguard public health, policymakers and healthcare providers rely on the availability and reliability of data about the relative costs and benefits of competing treatment options. One such an approach is based on cost effectiveness analysis (CEA) which is intended to be used as a combined metric of both the costs and health outcomes ...

BACKGROUND Laboratory testing in clinical practice is never a random process. In this study we evaluated testing bias for neutrophil counts in clinical practice by using results from requested and non-requested hematological blood tests. METHODS This study was conducted using data from the Utrecht Patient Oriented Database. This clinical database is unique, as it contains physician requested ...