Objectives: Belonging to Papaveraceae family, Glaucium vitellinum is one of the Persian endemic plants which has not been investigated biologically. The present paper focused on the assessment of the antibacterial and antifungal activities of the total methanol extract and alkaloid sub-fraction of the flowering aerial parts of G. vitellinum. Materials and Methods: The antibacterial and antifung...

Objective: Ipomoea mauritiana is used in both Ayurveda and folk medicine systems. The tuberous roots are known to be diuretic, depurative, carminative, and anthelmintic. The objective of the current study was to identify phenolic antioxidants from I. mauritiana using spectrophotometric and LC-MS analysis. Materials and Methods: An activity-guided fractionation and purification process was used t...

Background and objectives: Malaria is a remarkable cause of death in the world. Several ways are used by researchers to control or to decrease the detrimental effects of the disease, in which natural insecticides with less malaria vectors resistance and lower environmental damages are considered in last decades.The objective of this study was to assess the larvicidal activity of the whole flowe...

Background and objectives: Berberis vulgaris L (Berberidaceae) is a medicinal plant that is distributed in different parts of Iran; it is grown as a wild or cultivated plant. It has different pharmacological activities such as antioxidant, anti-inflammatory, anti-arrhythmic, sedative and anti-malaria effects. In this study, the anti-seizure activity of different fracti...

background and objectives: datura innoxiamilleris one of the two species of datura (solanaceae) which grow in iran. there are many reports of the biological activities of datura and in the present study the ability of datura innoxia for inhibiting angiogenesis was evaluated. methods: the methanol extract and petroleum ether, chloroform and methanol fractions of datura innoxia flowers were obtai...

BACKGROUND One of the main challenges for heterologous protein production by the methylotrophic yeast Pichia pastoris at large-scale is related to its high oxygen demand. A promising solution is a co-feeding strategy based on a methanol/sorbitol mixture during the induction phase. Nonetheless, a deep understanding of the cellular physiology and the regulation of the AOX1 promoter, used to gover...

Background and objectives: Cuminum cyminum from Apiaceae family is a common medicinal plant. The fruits of this plant are the second most popular spice after Piper nigrum in the world. It is used in cooking as flavoring and also it has been used for treatment of toothache, epilepsy, diarrhea,emphysema and gastrointestinal problems in Iranian traditional medici...

background and objectives: angiogenesis is essential for tumor survival. inhibiting angiogenesis could be a mechanism for hindering tumor development. numerous studies have now been focused on agiogenesis inhibitors and many of such studies have targeted plant materials. in the present study, crocus pallasii subsp. haussknechtii has been evaluated for anti-angiogenesis properties. methods: anti...

Rural dwellers in Nigeria often resort to herbal remedy and dietary control in the treatment of diabetes mellitus (DM). This work was undertaken to provide the rationale for the use of the leaves of Gogronema latifolium as a traditional antidiabetic agent. Methanol extract (ME) of the leaves of G. latifolium was prepared by soxhlet extraction while the aqueous extract (AE) was prepared by cold ...

BACKGROUND This study was aimed to evaluate antioxidant and α-glucosidase inhibitory activity, with a subsequent analysis of total phenolic and total flavonoid content of methanol extract and its derived fractions from Clinacanthus nutans accompanied by comprehensive phytochemical profiling. METHODS Liquid-liquid partition chromatography was used to separate methanolic extract to get hexane, ...