OBJECTIVE To examine the presentation, diagnosis, and appropriate management of renal clear cell carcinoma metastasis to the thyroid gland. METHODS We describe a clinical case of solitary thyroid metastasis from renal clear cell carcinoma and present a comprehensive review of the related English-language literature. Common patterns of presentation and generalized overall management recommenda...

OBJECTIVE We describe the case of a patient with metastatic breast cancer who presented with eyelid margin thickening and madarosis more suggestive of sebaceous cell carcinoma than metastatic disease. Histopathology confirmed metastatic breast adenocarcinoma. CASE REPORT A 59-year-old woman with a known history of metastatic breast carcinoma actively enrolled in a clinical trial presented wit...

hepatocellular carcinoma (hcc) is the most common, malignant tumor of the liver. hepatocellular carcinoma (hcc) commonly metastasizes to the lungs, abdominal lymph nodes, adrenal glands, or bones. distant lymph node metastases are rare in hepatocellular carcinoma. a 49-year-old male patient presented with right sided neck mass. on examination there was right cervical lymphadenopathy and hepatom...

OBJECTIVE To evaluate the diagnostic utility of Hep par-1 in differentiating hepatocellular carcinoma from metastatic carcinoma taking histopathology as a gold standard. STUDY DESIGN Comparative cross-sectional study. PLACE AND DURATION OF STUDY Pathology Department, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, from April 2007 to February 2008. METHODOLOGY Hep par-...

We evaluated the diagnostic value of hepatocyte nuclear factor 1 beta (HNF-1β) and napsin A for diagnosing ovarian clear cell carcinoma. Immunohistochemical EnVision was used to measure HNF-1β and napsin A expression in 38 cases of ovarian clear cell carcinoma, 30 cases of high-grade serous carcinoma, 22 cases of endometrioid adenocarcinoma, and 16 metastatic Krukenberg tumor cases. Then we fou...

clinically apparent cervical lymphadenopathy has been found at the initial presentation in 23 to 56 % of cases of papillary thyroid carcinoma. here we report tuberculous lymphadenitis mimicking metastatic lymph nodes from papillary thyroid carcinoma and suggest that tuberculosis apart from metastasis in papillary thyroid carcinoma should also be considered in the etiology of enlarged lymph node...

Invasive lobular carcinoma of the breast has similar patterns of metastatic disease when compared to invasive ductal carcinoma; however, lobular carcinoma metastasizes to unusual sites more frequently. We present a 65-year-old female with a history of invasive lobular breast carcinoma (T3N3M0) treated with modified radical mastectomy and aromatase-inhibitor therapy who underwent a surveillance ...

INTRODUCTION Invasive ductal and lobular carcinomas represent 67.9% and 6.3% of breast carcinoma, respectively. Metastatic breast cancer typically involves the lungs, bones, brain, and liver. Studies have shown differing patterns of metastatic spread between ductal and lobular carcinoma. Lobular carcinoma is more likely to metastasise to the gastrointestinal tract. CASE PRESENTATION We report...

Approximately 15% of renal cell carcinomas metastasize to the head and neck region. Here in, we report a rare case patient who underwent nephrectomy for carcinoma (RCC) ten years ago presented with metastatic on her lower lip. A 65-year-old woman rapidly growing mass Pathology resulted in metastasis. Although is uncommon, metastasis should be considered differential diagnosis vascular lesion ar...

Changes in the glycosylation of asparagine-linked oligosaccharides have been shown in various tumor cells, including human colon cancer. Attempts were made to elucidate the difference in Asn-linked oligo-saccharides attached to lysosomal membrane glycoproteins isolated from sublines of human colon carcinoma exhibiting high and low metastatic potentials in nude mice. Lysosomal membrane glycoprot...