The iron-dependent regulator (IdeR) protein in Mycobacterium tuberculosis, and its better characterized homologue, the diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae, are iron-dependent regulatory proteins that control gene expression in response to iron availability in bacteria. IdeR regulates several genes required for iron uptake and storage including those involved in th...

Spectropholornetrie technique is used to evaluate binding of the vanadium(1U) ion to a water solublecaruc[4] arene molecule in aqueous solution. On the basis of the calculated value formation constant at25rC.we found that the eomplexation of this metal on is very favored towards 25, 26, 27, 2Stetrahydroxy-5, 11, 17, 23-tetnmulphonalic acid-calix[0]areneGaussian 03 package.

reduce the MMT partial pressure to an even smaller value. It is obvious from the above that the po£-sibility of hazardous exposure of customers has to be much lower even than would be the case for TEL. When this is considered in light of the studies of Kehoe et al. in the 1960s on lead alkyls and service station attendants (who would have more exposure than self-service customers) in which it i...

Extensive ambient extraction of several metals from human hair compromises some assumptions concerning the binding of metals to hair and the biochemical process of metal incorporation into hair. Hair metal concentrations can reveal metal intoxications and metal deficiencies.The scalp hair selected for investigation included specimens of different colors from both sexes for various donor ages an...

recently, several studies have shown that the metal-fluoroquinolone complexes have more antibacterial and cytotoxic effects in comparison with free fluoroquinolones. these results may introduce new drugs for chemotherapy with fewer side effects. in this work a bidentated zinc (ii) complex with ofloxacin (ozc) was synthesized and cytotoxicity activities and dna binding of the resulted complex wa...

A semi-automated, rational design strategy has been used to introduce a family of seven single, mononuclear Cys2His2 zinc sites at various locations in the hydrophobic core of Escherichia colithioredoxin, a protein that is normally devoid of metal centers. The electronic absorption spectra of the CoII complexes show that five of these designed proteins bind metal with the intended tetrahedral g...

The movement of a copper ion inside the cavity of cryptands having two distinct metal binding sites at each end is linked to a fluorescence ON-OFF process in a reversible manner, providing a new way of fluorescence switching.

porophyrins and their metal derivatives are strong dna binders with association constant of  to  . some of these compounds have been used for the radiations sensitization therapy of cancer and are targeted to interact with cellular dna. binding of porphyrins to dna changes the expectral and other physic chemical characteristic of porphyrins, the mode of binding can be extracted from inspection ...

The predominant species of the cyanobacterial metalloregulatory protein SmtB as observed by ESI-MS is a dimer with all four zinc binding sites occupied.