نتایج جستجو برای: metabolic profiling

تعداد نتایج: 296594  

Journal: :Frontiers in Aging Neuroscience 2020

Journal: :Annals of nutrition & metabolism 2012
Steven H Zeisel

One of the underlying mechanisms for metabolic individuality is genetic variation. Single nucleotide polymorphisms (SNPs) in genes of metabolic pathways can create metabolic inefficiencies that alter the dietary requirement for, and responses to, nutrients. These SNPs can be detected using genetic profiling and the metabolic inefficiencies they cause can be detected using metabolomic profiling....

Journal: :Bioinformatics 2013
Dhwani K. Desai Harald Schunck Johannes W. Löser Julie LaRoche

MOTIVATION The sheer scale of the metagenomic and metatranscriptomic datasets that are now available warrants the development of automated protocols for organizing, annotating and comparing the samples in terms of their metabolic profiles. We describe a user-friendly java program FROMP (Fragment Recruitment on Metabolic Pathways) for mapping and visualizing enzyme annotations onto the Kyoto Enc...

Journal: :Cancer research 2012
Prakash Chinnaiyan Elizabeth Kensicki Gregory Bloom Antony Prabhu Bhaswati Sarcar Soumen Kahali Steven Eschrich Xiaotao Qu Peter Forsyth Robert Gillies

Although considerable progress has been made toward understanding glioblastoma biology through large-scale genetic and protein expression analyses, little is known about the underlying metabolic alterations promoting their aggressive phenotype. We conducted global metabolomic profiling on patient-derived glioma specimens and identified specific metabolic programs differentiating low- and high-g...

2012
Prakash Chinnaiyan Elizabeth Kensicki Gregory Bloom Antony Prabhu Bhaswati Sarcar Soumen Kahali Steven Eschrich Xiaotao Qu Peter Forsyth Robert Gillies

Although considerable progress has been made toward understanding glioblastoma biology through largescale genetic and protein expression analyses, little is known about the underlying metabolic alterations promoting their aggressive phenotype. We conducted global metabolomic profiling on patient-derived glioma specimens and identified specific metabolic programs differentiating lowand high-grad...

Journal: :Circulation: Cardiovascular Genetics 2017

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