Mesothelioma incidence is high in certain villages on the Anatolian plateau in Turkey, where environmental exposure includes erionite, a form of zeolite fibers, from the local volcanic tuff. Previous studies of this exposure were cross-sectional or with a follow-up period of only a few years. A prospective study of residents of two exposed and one nearby control village was initiated in 1979 an...

Malignant pericardial mesothelioma is a rare and progressive cardiac tumor. There is no established standard treatment and the prognosis is poor. Most patients were retrospectively diagnosed from surgery or autopsy due to absence of specific clinical manifestation. Most patients with pericardial mesothelioma have demonstrated constrictive physiology on echocardiography or cardiac catheterizatio...

BACKGROUND Malignant pleural mesothelioma is considered an almost incurable tumour with increasing incidence worldwide. It usually develops in the parietal pleura, from mesothelial lining or submesothelial cells, subsequently invading the visceral pleura. Chromosomal and genomic aberrations of mesothelioma are diverse and heterogenous. Genome-wide profiling of mesothelioma versus parietal and v...

background malignant pleural mesothelioma (mpm) is an uncommon neoplasm. mpm occurs more frequently in patients born or living in certain villages of turkey. objectives we aimed to review radiological findings of mpm. patients and methods we reviewed the ct findings in 219 biopsy-proven mpm patients admitted to our clinic between 1993 and 2008. results the most common ct findings included pleur...

Mesothelial lesions pose considerable diagnostic challenges not only because benign tumours, reactive proliferations and malignant mesothelioma can mimic one another, but also because the morphological patterns displayed by malignant mesothelioma can simulate a variety of epithelial and non-epithelial malignancies. Immunohistochemical markers can aid in distinguishing epithelioid malignant meso...

A study was made of 93 cases of mesothelioma who died in 1976 in the United Kingdom. Lung tissue was available for mineral fibre analysis from 86 of these cases, and also from 29 cases of cerebrovascular disease and 27 cases of bronchial carcinoma, matched for place of death, age and sex with the mesothelioma cases. It was observed that: (1) mesothelioma patients had more amphibole fibres in th...

The hyaluronan production by three human malignant mesothelioma cell lines and nine primary human mesothelial cell types was determined. The mesothelioma cell lines produced only minute amounts of hyaluronan (less than 0.1 microgram/10(6) cells/48 h) whereas mesothelial cells synthesized large quantities of hyaluronan (10-72 micrograms/10(6) cells/48 h). Conditioned media from the mesothelioma ...

Primary malignant peritoneal mesothelioma with clear cell subtype is a rare malignancy few previously reported cases. We present 63-year-old female who presented abdominal distention and was diagnosed of the peritoneum an isolated metastasis to liver. The patient underwent surgical resection greater than 50 cm mass en-bloc partial liver gastric uneventful post-operative course. There are establ...

Mesothelioma is a relatively rare tumor arising from the pleura, most notably associated with exposure to asbestos1. Typically, mesothelioma is a locally aggressive tumor with a poor outcome in the order of months from the time of diagnosis2. Although cases of distant metastases of mesothelioma have been documented in the literature, this tumor has less reported cases of metastases than other m...

OBJECTIVES To pathologically distinguish mesothelioma from lung carcinoma, particularly adenocarcinoma. METHODS We conducted immunohistochemical analyses on clinical specimens, including 26 cases of mesothelioma, 28 cases of lung adenocarcinoma, and 33 cases of lung squamous cell carcinoma. RESULTS We found that CD90 expression was useful in making a differential diagnosis between epithelio...