Synthesis of NS1 and NS2 peptide fragment hepatitis C virus polyprotein was carried out on a terpolymer- polystyrene, N-vinylpyrrolidone, 1,6-hexanediol diacrylate resin (PS-NVP-HDDA). The radical aqueous suspension polymerisation resulted in the resin, that exhibited high swelling capacity various solvents. peptides were synthesized step-wise by Fmoc strategy, established with amino acid analy...

Merrifield resin was converted to various dialkyl-trihydroxybenzaldehyde resins and then to different bound imine resins. Fluorescence spectroscopy was used to continuously monitor the intermediates performed on the resins. Using fluorescent label (dansyl chloride) information on the kinetics of the amine cleavage was obtained. This study demonstrated that direct measures of fluorescence intens...

On page 144 of (3], a (see Gutman[l]), formulated as follows:

Recently we reviewed the work of Nlels K. Jerne, C&ar Milstein, and Georges J.F. Kohler, who shared the 1984 Nobel Prize in medicine. 1 We also examined the work of Carlo Rubbia and Simon van der Meer, joint recipients of the physics prize, and that of R. Bruce Merrifield, who was awarded the chemistry prize.z In this essay we review the achievements of the prizewinners in economics and literat...

The local stellar kinematics of the Milky Way, parameterized by the Oort constants A and B, depend on the local gradient of the rotation curve, its absolute value (Θ0), and the distance to the Galactic center (R0). The surface density of interstellar gas in the Milky Way varies non-monotonically with radius, and so contributes significantly to the local gradient of the rotation curve, and the O...

Alkaloids such as cinchonidine, quinine and N-methylephedrine have been N-alkylated using polymeric benzyl halides or co-polymerized and then N-alkylated, thus affording a series of polymer-supported chiral ammonium salts which have been employed as phase-transfer catalysts in the asymmetric benzylation of an N-(diphenylmethylene)glycine ester. These new polymeric catalysts can be easily recove...

2,3-Dichloro-1,4-naphthoquinone and tetrabromoor tetrachloro-1,4-benzoquinone were converted into pyridinium enolate betaines by reaction with pyridine or 4,4′-bipyridine. The reaction conditions were applied to poly-(4-vinylpyridine) and a modified Merrifield resin to obtain functionalized polymeric materials. These were examined in thermogravimetric analyses. Reversible photocatalytic electro...