It is well known that mercury is ac cumulated in the kidney and causes renal failure. Mercury has been a subject of extensive study, but a definite mechanism for its biochemical toxicity remains to be elucidated. In a previous paper (1), we reported that mersalyl (mercurial diuretic) had a more powerful stimulatory effect on the lipid peroxidation in renal cortical mito chondria than any other ...

mercury is one of the three major environmental metal poisons, and mercuric chloride is a highly reactive compound which can harm cells by a variety of mechanisms including direct interaction with sulphydryl groups of proteins and enzymes, therefore affecting the enzymatic activity. this study focused on the effect of hg++ on horseradish peroxidase (donor: hydrogen peroxide oxidoreductase, ec 1...

With the advent of modern ophthalmic treatment the use of mercury preparations in ophthalmology has almost been relegated to past history, but mercurous chloride (calomel) is still occasionally used as an insufflation into the eyes, especially in such conditions as phlyctenular keratoconjunctivitis. Recently we saw a case wherein mercuric chloride (HgCl2) was mistaken for calomel and dusted int...

The renal excretion of renin infused intravenously was studied in anesthetized rats. The renin in the urine was adsorbed onto DEAE cellulose and selectively eluted for separate assay on the rat blood pressure preparation. The influence of saline loading, furosemide, mercuric chloride, and maleic acid was determined by following the changes in renin excretion. Both mercuric chloride and maleic a...

abstract heavy metals are the important pollution which there is in the aquatic ecosystems. today, with advances in technology have increased the pollution therefore it is important to assessment the risks. the aim of this study was acute toxicity effects of mercury chloride, lead chloride and zinc chloride in silver carp fish. in this study there were 5 treatments for lead chloride and mercury...

The organomercurial, thimerosal, is at the center of medical controversy as a suspected factor contributing to neurodevelopmental disorders in children. Many neurotoxic effects of thimerosal have been described, but its interaction with principal excitatory and inhibitory neurotransmiter systems is not known. We examined, using electrophysiological recordings, thimerosal effects on GABA and NMD...

dialysis produced an effective biochemical adjustment and ultrafiltration of excess fluid. A chest X-ray subsequent to this dialysis demonstrated no evidence of pulmonary cedema. Diuresis commenced I4 days after the ingestion of mercuric chloride and an uneventful recovery ensued. Discussion Pulmonary cedema complicating acute renal failure is subsequent to hypervolemia produced by overhydratio...