A 28-year-old man who had suffered a traffic accident underwent conservative management for diffuse axonal injury and intracerebral hemorrhage in the left temporal lobe. Brain MRI (3 months after onset; fig. 1) showed a leukomalactic lesion in the corpus callosum and an old hemorrhage at the left temporal lobe and pons. The Memory Assessment Scale score for verbal memory (86: 18th percentile) w...

The prognostic ability of global white matter and gray metabolite ratios following pediatric traumatic brain injury (TBI) their relationship to 12-month neuropsychological assessments intelligence quotient (IQ), attention, memory is presented. Three-dimensional proton magnetic resonance spectroscopic imaging (MRSI) in subjects with complicated mild (cMild), moderate, severe TBI was acquired acu...

Objective: To present pre-injury, injury-related, work-related and post-injury characteristics, to compare patients with without traumatic intracranial abnormalities, in a treatment-seeking sample persistent post-concussion symptoms (PPCS) after mild-to-moderate TBI.Methods: Cross-sectional design the context of specialized TBI outpatient clinic. Eligible were aged 18–60 years, employed ? 50% a...

Persistent neuropathic pain is a frequent consequence of peripheral nerve injuries, particularly in the elderly. Using the IntelliCage we studied if sciatic nerve injury obstructed learning and memory in young and aged mice, each in wild type and progranulin deficient mice, which develop premature signs of brain aging. Both young and aged mice developed long-term nerve injury-evoked hyperalgesi...

BACKGROUND Although cardiac arrest (CA) is commonly cited as a cause of amnesia, patients referred to the authors' center with a diagnosis of "amnesia" after CA rarely have isolated memory deficits. OBJECTIVE To determine whether CA is a cause of pure amnesia and to assess patterns of cognitive deficits after CA. METHODS The authors used cognitive assessment of 11 consecutive patients refer...

Studies of young children with early unilateral brain injury have suggested that while hemispheric differences in visuospatial processing appear to be present early in development, the young brain is better able to compensate for injury than when the injury occurs later, after networks have been established. The aim of this study was to determine if this pattern continues later in development w...

Advances in functional imaging technology and cognitive neuropsychology have resulted in paradigms in which participants can perform cognitive tasks during functional image acquisition. We will discuss the application of two approaches (oxygen-15 positron emission tomography and functional magnetic resonance imaging) that have recently been used to examine components of learning and memory foll...