نتایج جستجو برای: membrane damaging
تعداد نتایج: 402011 فیلتر نتایج به سال:
The contribution of low-frequency and damaging genetic variants associated with platelet function to ischemic stroke (IS) susceptibility remains unknown. We employed a deep re-sequencing approach in Polish patients in order to investigate the contribution of rare variants (minor allele frequency, MAF < 1%) to the IS genetic susceptibility in this population. The genes selected for re-sequencing...
Many isothiocysanates (ITC) are promising cancer-preventive agents, and induction of apoptosis is one of their underlying mechanisms of action. We recently found that caspase-9 was preferentially activated over other initiator caspases in human bladder cancer UM-UC-3 cells. We report here that caspase-9 activation is the major step leading to ITC-induced apoptosis in this cell line. More import...
Induction of apoptosis by DNA-damaging agents such as 1-beta-D-arabinofuranosylcytosine (Ara-C) includes the activation of Lyn protein tyrosine kinase. We have previously established that Ara-C-induced activation of Lyn results in its binding to a neutral sphingomyelinase (SMase) and is requisite for its stimulation and the induction of apoptosis in U937 cells. However, the spacio-temporal orga...
Introduction: To attach the fetus to the endometrial epithelium, the endometrium should be affected and allowed by the steroid hormones secreted from the ovary. Thus, the endometrium is then subject to several structural and biochemical changes. Implantation involves the embedment, adhesion and invasion steps that specific receptors are engaged in that. The role of membrane receptors in uterine...
Designing an emulsified matrix formulation in the laboratory, ratios of emulsifier span-80 and T-152 were 1:0, 2:1, 1:2, 0:1 respectively. Then preparation was added by 0.04% Fe2+ impurities emulsion matrix. Based on water-soluble test method, we used ultrasonic instrument to focus containing impurities. The results show that crystallization amount adding is more than not .Impurities has damagi...
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