kcnk2 was previously shown to regulate immune-cell trafficking into the central nervous system (cns). kcnk2-/- mice demonstrated a more severe disease course in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis, due to an increased immune-cell migration into the cns. an upregulation of the cellular adhesion molecules icam1 and vcam1 on brain endothelial cells in k...

introduction: in the present investigation, we aimed to study the effect of different concentrations of ascorbate/vitamin c, on membrane integrity, viability, and acrosome reaction of human spermatozoa in presence of ferrous (fe2+) ions as lipid peroxidation (lpo) promoter. material and methods: we used 12 semen samples from healthy donors in shahrekord. the samples were then washed twice with ...

Embryonic Hematopoiesis In article number 2205345, Fudi Wang, Junxia Min, and co-workers identify demonstrate indispensable function of zinc transporter SLC39A10 (ZIP10) its mediated homeostasis for maintaining the survival fetal hematopoietic stem/progenitor cells. As most important importer on cell membrane stem cells, ZIP10 functions as a gatekeeper (like vacuum to transport across membrane)...

Utilization of membrane humidifiers is one of the methods commonly used to humidify reactant gases in polymer electrolyte membrane fuel cells (PEMFC). In this study, polymeric porous membranes with different compositions were prepared to be used in a membrane humidifier module and were employed in a humidification test. Three different neural network models were developed to investigate several...

Background: Expansion of the use of magnetic fields in metals, mining, transport, research, and medicine industries has led to a discussion about the effects of magnetic fields and whether their strength is negligible. The aim of this study was to investigate the effects of magnetic field on the viability and proliferation rate of HeLa cells. Materials and methods: We studied the effects of ma...

Auto-reactive cells-mediated immune responses are responsible for the current tissue damages during autoimmunity. Accordingly, functional modulation of auto-reactive cells has been a pivotal aim in many of recent studies. In the current study, we investigated the possibility for insertion of regulatory molecules onto auto-reactive cells through exosomal nano-shuttles as a novel approach for phe...

This article evaluates the effect of membrane active channel-forming polyene antibiotic (PA) of levorin and its alkyl derivatives on the muscle performance. The membrane channels of muscle cells are capable to transport ions of potassium, sodium, and calcium. In the period of an intensive muscle exercise, the necessity for organic substrates increases and these channels start to work with the g...

Background  Wisdom teeth are usually removed as a routine procedure for therapeutic or prophylactic reasons. Developing wisdom teeth are easy accessible source of stem cells during the adulthood which could be obtained. Methods  Search of the PubMed for stem cells and tooth was done. An inclusion criterion was extract of stem cells from wisdom tooth. Results  Stem cells can be obtained fro...