Drosophila adult females but not males contain high levels of the steroid hormone ecdysone, however, the roles played by steroid signaling during Drosophila gametogenesis remain poorly understood. Drosophila germ cells in both sexes initially follow a similar pathway. After germline stem cells are established, their daughters form interconnected cysts surrounded by somatic escort (female) or cy...

PiMP (The Pimpant Management Protocol), was a tremendous step forward in the management of Hoares. However, PiMP has been shown to only work effectively in the local area, with a small cluster of clients. Recently, much work has been performed in the arena of Escort Services, an attempt to generalize the work of Hoare Monitors to the wide area. We present an algorithm for discovering such servi...

jcb.201007018”> Wemmer et al. show. Like a big brother, Bro1 protects a protein complex that helps pinch off vesicles. The ESCRT-III complex serves as a pair of molecular scissors that cuts cell membranes, helping to separate dividing cells and enabling viruses such as HIV to bud from the cell surface. The complex also helps endosomes fashion intralumenal vesicles (ILVs), which hold wo...

Human trafficking is a global epidemic affecting millions of people across the planet. Sex trafficking, the dominant form of human trafficking, has seen a significant rise mostly due to the abundance of escort websites, where human traffickers can openly advertise among at-will escort advertisements. In this paper, we take a major step in the automatic detection of advertisements suspected to p...

PURPOSE Recovery and discharge following ambulatory surgery are important components of the ambulatory surgery experience. This review provides contemporary perspectives on the issues of discharge criteria, fast-tracking, patient escort requirements, and driving after ambulatory anesthesia. SOURCE A search was performed in the Cochrane Central Register for Controlled Trials, MEDLINE(R), EMBAS...

Drosophila Piwi is the founding member of a gonadal clade of Argonaute proteins that serve as silencing effectors for ∼26-32 nt Piwi-interacting RNAs (piRNAs) [1], and piwi mutants exhibit dramatically rudimentary ovaries [2]. It was proposed that somatic Piwi maintains germline stem cells (GSCs) by promoting Dpp signaling, presumably via cap cells that form the somatic niche for GSCs [3-5]. Ho...