OBJECTIVE To determine the impact of endoesophageal ultrasound-guided fine-needle aspiration (EUS-FNA) on management of thoracic malignancies. METHODS One hundred and twenty patients referred for invasive diagnostic and resection of thoracic malignancies were studied prospectively. Negative and inconclusive EUS-FNA findings were assessed by video-assisted mediastinoscopic lymphadenectomy (VAM...

castleman’s disease, giant lymph node hyperplasia, is a kind of benign lymphoproliferative disease with gentle behavior. its etiology and prevalence are unclear. this rare disease is usually found in mediastinal area asymptomatically and incidentally. it is also rare to see this tumor in the retroperitoneum. in this study, we have introduced a 34-year-old woman who referred just with occasional...

Mediastinal parathyroid disease requiring a thoracic surgical approach is a rare and challenging clinical entity. The objective of this study was to review our experience treating these patients, highlighting the importance of a multidisciplinary approach. Seven patients required a thoracic approach for mediastinal parathyroid disease between 1999 and 2010. All patients achieved biochemical cur...

BACKGROUND Constituent part of radical lung resection for lung cancer is a dissection of mediastinal lymph nodes. Lymphadenectomy is a standard procedure in an assessment of clinical stage of the disease. The aim of the study was to map metastasizing of bronchogenic non-small cell lung carcinoma into homolateral mediastinal lymph nodes and to assess the importance of mediastinal lymphadenectomy...

Residual mediastinal masses are frequently observed in patients with Hodgkin disease (HD) after completed therapy, and the discrimination between active tumor tissue and fibrotic residues remains a clinical challenge. We studied the diagnostic value of metabolic imaging by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) in detecting active mediastinal disease and predicting rela...

STUDY OBJECTIVE We hypothesized that transoesophageal endoscopic ultrasound guided fine needle aspiration (EUS-FNA) has the potential to be a valuable and accurate new diagnostic technique for mediastinal restaging in non-small cell lung cancer (NSCLC) after induction chemotherapy. The current restaging modalities either have a low diagnostic accuracy (computed tomography (CT) scan of the thora...

there has been a highly significant increase in the number of patients with malignant mediastinal tumors in the last four decades. since these lesions are infrequently encountered and there are very few reports in iran concerning this issue, we performed this study to review our institutional experience of medias-tinal masses and to compare differences in the clinical spectrum between our study...

The main purpose of staging in non-small cell lung cancer (NSCLC) is to assess mediastinal lymph node involvement, with thoracic CT being the main non-invasive test for this. However, given that up to 15% of patients who show no mediastinal lymph node involvement in the CT have lymph node metastasis during surgery, other examinations are required. Endoscopic ultrasonography guided fine-needle a...

Abstract Background The aim of this study was to evaluate sensitivity and specificity of mediastinal sonography, and compared with CT, in detection of anterior mediastinal neoplasms. Materials and Methods The sonography with convex probes (5.0 and 7.5 MHz) was done prospectively for 34 patients (from 2 to 25 years old) with mediastinal mass. The results were compared with the results of ...

Thoracic extramedullary hematopoiesis (EMH) is a rare disease entity that is usually associated with hematologic disorders, such as myelodysplastic or hemolytic disease. Because thoracic EMH is usually encountered as a mass during radiologic examinations, it should be differentiated from posterior mediastinal neurogenic tumors. Here, the authors report a case of EMH associated with hereditary s...