background: ventilator-associated pneumonia (vap) is the most common nosocomial (hospital acquired) infection among patients undergoing mechanical ventilation. it increases mortality rate, duration of mechanical intubated ventilation, and hospitalization in the intensive care units (icus). this review study aims to determine the proper gradient of a hospital bed in preventing vap in patients ho...

objectives: to compare the results of early versus late tracheostomy in trauma patients admitted to intensive care unit (icu). methods: this was case control study being performed at a major trauma centre in shiraz, iran including 120 trauma patients admitted to icu during a 2-year period and underwent tracheostomy during their icu stay. the patients were categorized into two groups of the earl...

background neonatology has evolved with respect to the needs of premature infants for special care. one of the major problems in premature infants is that their lungs are not developed adequately to fulfill newborns’ needs. there is a broad spectrum of strategies for management of respiratory problems in premature infants. in this study, we aimed to determine the best strategies against respira...

Prolonged mechanical ventilation results in diaphragmatic oxidative injury, elevated proteolysis, fiber atrophy, and reduced force-generating capacity. We tested the hypothesis that antioxidant infusion during mechanical ventilation would function as an antioxidant to maintain redox balance within diaphragm muscle fibers and therefore prevent oxidative stress and subsequent proteolysis and cont...

RATIONALE Mechanical ventilation is known to induce ventilator-induced diaphragm dysfunction. Patients submitted to mechanical ventilation often receive massive doses of corticosteroids that may cause further deterioration of diaphragm function. OBJECTIVES To examine whether the combination of 24 hours of controlled mechanical ventilation with corticosteroid administration would exacerbate ve...

results sixty patients were involved in this study. in asv mode, values including peak airway pressure (p-peak), end-tidal carbon dioxide (etco2), tidal volume and respiratory dead space were significantly lower than simv mode. although the mean value for dynamic compliance had no significant difference in the two types of ventilation, it was better in asv mode. methods in a crossover study, pa...

For the busy clinician, educator, or manager, it is becoming an increasing challenge to filter the literature to what is relevant to one's practice and then update one's practice based on the current evidence. The purpose of this paper is to review the recent literature related to invasive mechanical ventilation, noninvasive ventilation, and cystic fibrosis. These topics were chosen and reviewe...