نتایج جستجو برای: mda mb468
تعداد نتایج: 20691 فیلتر نتایج به سال:
PURPOSE The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) markedly potentiates the efficacy of many cytotoxic agents against several human cancer xenografts, irrespective of tumor EGFR expression levels. We subsequently investigated the extent to which ZD1839 might improve radiation therapy (RT) in similar animal models of human cancer within the limits of tolerance...
(MAP2K3, MKK3) is a member of the dual-specificity protein kinase group (MKK) that belongs to the mitogen-activated protein kinase (MAPK) signaling pathway. Following different forms of stressful stimuli and inflammatory cytokines, MKK3 is activated through phosphorylation on serine and threonine residues at sites Ser189 and Thr193 by MKKK proteins (MEKK 1-4) [1]. Activated MKK3 phosphorylates ...
دیابت ملیتوس یک اختلال متابولیکی مزمن است که علت آن نقص در ترشح انسولین (نوع i) یا فعالیت انسولین در سطح رسپتورها و یا هردو (نوع ii) است. از دیرباز گیاهان دارویی در درمان بیماری دیابت بکار رفته اند. اما بررسی علمی اثر بخشی و عوارض احتمالی این گیاهان دارویی از اهمیت زیادی برخوردار است. مشخص شده اکثریت گیاهان دارویی که در درمان دیابت استفاده می شوند دارای اجزا فعال بیولوژیکی (آلکالوئیدی، فلاوونوئ...
antiepileptic and antioxidant effect of brassica nigra on pentylenetetrazol-induced kindling in mice
considering the high rate of epilepsy today, with respect to the insufficiency of the available therapies, new strategies and methods are recommended for medical treatment of epileptic patients. therefore, the present study experimentally investigated the anticonvulsant effect of a herbal medicine candidate brassica nigra, by using kindling method. sixty male mice were randomly selected and div...
Objectives To determine the proportion of patients with psoriatic arthritis in the Adalimumab Effectiveness in Psoriatic Arthritis trial achieving minimal disease activity (MDA) and its individual components at 1 or more visits over 144 weeks, identify baseline predictors of MDA achievement, and evaluate the association of MDA status with independent quality of life (QoL)-related patient-report...
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