Monocyte chemoattractant protein-1 (MCP-1) and transforming growth factor (TGF)-beta1 are critical mediators of renal injury by promoting excessive inflammation and extracellular matrix deposition, thereby contributing to progressive renal disease. In renal disease models, MCP-1 stimulates the production of TGF-beta1. However, a potential role for TGF-beta1 in the regulation of MCP-1 production...

BACKGROUND/AIMS Chemokines are a family of low molecular weight cytokines that attract and activate leucocytes. The CC chemokines act on eosinophils, basophils, monocytes, and lymphocytes, suggesting that they play an important part in allergic diseases. The aims of this study were to investigate the expression of the CC chemokines, RANTES, eotaxin, monocyte chemotactic protein (MCP) 1, MCP-2, ...

Chemotactic cytokines of the CC subfamily (CC chemokines) are considered as major mediators of allergic inflammation owing their actions on basophil and eosinophil leukocytes. The monocyte chemotactic protein (MCP) 1 is a potent inducer of mediator release from basophils but is inactive on eosinophils. To obtain information on the structural determinants of the activities of MCP-1, we have synt...

Monocyte migration and activation are regulated by monocyte chemoattractant protein-1 (MCP-1). Prior studies have shown MCP-1 expression is modulated by a variety of ligands that act through extracellular receptors. In the current study, we show 9-cis retinoic acid (RA), a ligand for the nuclear hormone receptor retinoid X receptor (RXR) and retinoic acid receptor (RAR), markedly induces the ex...

Data on estimating the vertical dimension of occlusion（VDO）for fabricating a complete denture based tongue pressure, which is related to masticatory and swallowing functions, are scarce. This study aimed examine changes in pressure raising or lowering VDO from most comfortable position（MCP）. Ten edentulous, including Eichner C3, patients with existing dentures（six men four women; mean age, 78.6...

Monocyte chemoattractant protein-1 (MCP-1) is a potent chemotactic agent for monocytes and other cells and is thought to be involved in atherosclerosis, recruiting monocytes to the subendothelial space or to the site of inflammation. Angiotensin II has been demonstrated, at least in animal models, to stimulate MCP-1 expression. We investigated the effect of the angiotensin II type 1 (AT1) recep...

BACKGROUND/AIMS The degree of tubular atrophy and interstitial fibrosis (IFTA) is an important prognostic factor in glomerulonephritis. Imbalance between pro-inflammatory cytokines such as monocyte chemoattractant protein- 1 (MCP-1) and protective cytokines such as epidermal growth factor (EGF) likely determine IFTA severity. In separate studies, elevated MCP-1 and decreased EGF have been shown...

The Annurca type is an historical Italian apple fruit probably native to the Campania region. These fruits are harvested before a full maturity stage and go through open-field reddening process. Products based on 1-methylcyclopropene (1-MCP) widely used in postharvest improve quality avoid disorders controlled atmosphere. In this work, we tested impact of 1-MCP traditional system by analyzing t...

The tables of the appendix provide additional numerical results. Table 1 summarizes simulation results for Q-SCAD, LS-SCAD, Q-MCP, LS-MCP with sample sizes 50, 100 and 200 for modeling the 0.7 conditional quantile for the heteroscedastic error setting described in Section 4 of the main paper. The MCP approaches, Q-MCP and LS-MCP, are the equivalent of Q-SCAD and LS-SCAD with the SCAD penalty fu...

Monocyte chemoattractant protein-1 (MCP-1) has been demonstrated to play a role in tumor progression. The present study examined the MCP-1 expression of colorectal liver metastases and determined whether MCP-1 is related to tumor progression and is a predictive marker for survival after hepatic resection of colorectal liver metastases. Eighty-seven patients with colorectal liver metastases were...