Introduction: Brachytherapy is a type of radiotherapy in which radioactive sources are used in proximity of tumors normally for treatment of malignancies in the head, prostate and cervix. Materials and Methods: The Cs-137 Selectron source is a low-dose-rate (LDR) brachytherapy source used in a remote afterloading system for treatment of different cancers. This system uses active and inactive sp...

introduction: brachytherapy is a type of radiotherapy in which radioactive sources are used in proximity of tumors normally for treatment of malignancies in the head, prostate and cervix. materials and methods: the cs-137 selectron source is a low-dose-rate (ldr) brachytherapy source used in a remote afterloading system for treatment of different cancers. this system uses active and inactive sp...

introduction: ophthalmic plaque radiotherapy using i-125 radioactive seeds in removable episcleral plaques is often used in management of ophthalmic tumors. radioactive seeds are fixed in a gold bowl-shaped plaque and the plaque is sutured to the scleral surface corresponding to the base of the intraocular tumor. this treatment allows for a localized radiation dose delivery to the tumor with a ...

Currently, the use of blood irradiation for inactivating pathogenic microbes in infected blood products and preventing graft-versus-host disease (GVHD) in immune suppressed patients is greater than ever before. In these systems, dose distribution and uniformity are two important concepts that should be checked. In this study, dosimetry of the gamma chamber blood irradiator model Gammacell 3000 ...

Accuracy of treatment planning systems may significantly influence the efficacy of brachytherapy. The purpose of this work is a detailed, varied and independent evaluation of an in-house brachytherapy treatment planning software called STPS. Operational accuracy of STPS was investigated. Geometric tests were performed to validate entry and reconstruction of positional information from scanned o...

An x-ray computed tomography (CT) simulator based on the Monte Carlo N-particle radiation transport computer code (MCNP4C) was developed for simulation of both fan- and cone-beam CT scanners. A user-friendly interface running under Matlab 6.5.1 creates the scanner geometry at different views as MCNP4C's input file. The full simulation of x-ray tube, phantom and detectors with single-slice, mult...

In this study, dose rate distribution around a spherical 137Cs pellet source, from a low-dose-rate (LDR) Selectron remote afterloading system used in gynecological brachytherapy, has been determined using experimental and Monte Carlo simulation techniques. Monte Carlo simulations were performed using MCNP4C code, for a single pellet source in water medium and Plexiglas, and measurements were pe...

OBJECTIVE The passage of ionizing radiation in living cells creates clusters of damaged nucleotides in DNA. In this study, DNA strand breaks induced by the beta particle of iodine-131 (I-131), have been determined experimentally and compared to Monte Carlo simulation results as a theoretical method of determining(131)I damage. MATERIALS AND METHODS In this experimental study, in order to crea...